ID A0A021VPY8_9CELL Unreviewed; 442 AA.
AC A0A021VPY8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=N866_02210 {ECO:0000313|EMBL:EYR63216.1};
OS Actinotalea ferrariae CF5-4.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Cellulomonadaceae;
OC Actinotalea.
OX NCBI_TaxID=948458 {ECO:0000313|EMBL:EYR63216.1, ECO:0000313|Proteomes:UP000019753};
RN [1] {ECO:0000313|EMBL:EYR63216.1, ECO:0000313|Proteomes:UP000019753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF5-4 {ECO:0000313|EMBL:EYR63216.1,
RC ECO:0000313|Proteomes:UP000019753};
RA Chen F., Li Y., Wang G.;
RT "Actinotalea ferrariae CF5-4.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYR63216.1}.
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DR EMBL; AXCW01000113; EYR63216.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A021VPY8; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000019753; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF1; ISOCHORISMATE SYNTHASE MENF; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000019753}.
FT DOMAIN 174..432
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 442 AA; 45540 MW; 2A773EE2D12C4F72 CRC64;
MTVVRTVPAP GVGPLSPLRR AVAGPVVSRT VAVDPANLPG DLLRLLPAEG GLAWVRRGEG
VVAWGELLRV ETDGADRFAD AEDAWRALMA TAVVRDEVGV PGSGPVAFGS FAFAAGSPSG
GVLVVPRVVV GRRGGAAWVT TLDLGAVSAP PALRPTDAPA APGAVTYDDG ALSAEGWQDA
VRRAVEAIRA GALDKVVLAR DLLARTGAPL DPRWVLGRLA DDYASCWTFA VDGLLGATPE
LLLRSEKGLV TSRVLAGTIR RTGDDEADMA RAAILAHSSK DLEEHEYAVE SLTRALGPFC
SSTNVPETPF VLHLPNVLHL ATDVTGVLRA DGDAHVHPTS LGLAAALHPT AAVAGTPTDA
ACALIGEVEG MDRARYAGPV GWMGADGDGE WGIALRSAEL DPADPHRLRL FAGCGIVAAS
DPAAELAESE AKLEPMRSAL GS
//
