ID A0A022KVZ8_9MICO Unreviewed; 283 AA.
AC A0A022KVZ8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EYT48937.1};
GN ORFNames=D641_0109855 {ECO:0000313|EMBL:EYT48937.1};
OS Brachybacterium muris UCD-AY4.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=1249481 {ECO:0000313|EMBL:EYT48937.1, ECO:0000313|Proteomes:UP000019754};
RN [1] {ECO:0000313|EMBL:EYT48937.1, ECO:0000313|Proteomes:UP000019754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCD-AY4 {ECO:0000313|EMBL:EYT48937.1,
RC ECO:0000313|Proteomes:UP000019754};
RX PubMed=23516213;
RA Lo J.R., Lang J.M., Darling A.E., Eisen J.A., Coil D.A.;
RT "Draft genome sequence of an Actinobacterium, Brachybacterium muris strain
RT UCD-AY4.";
RL Genome Announc. 1:E0008613-E0008613(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT48937.1}.
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DR EMBL; AORC01000011; EYT48937.1; -; Genomic_DNA.
DR RefSeq; WP_017823499.1; NZ_AORC01000011.1.
DR AlphaFoldDB; A0A022KVZ8; -.
DR STRING; 1249481.D641_0109855; -.
DR HOGENOM; CLU_011276_9_1_11; -.
DR OrthoDB; 213853at2; -.
DR Proteomes; UP000019754; Unassembled WGS sequence.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR039793; UROS/Hem4.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019754}.
FT DOMAIN 29..270
FT /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT synthase"
FT /evidence="ECO:0000259|Pfam:PF02602"
SQ SEQUENCE 283 AA; 29888 MW; BC2EFDB1EE97EE79 CRC64;
MSASPESPRL SDALEGRRIL LAVDRRTGEL SAALERHGAQ VSVAAALTNI PHVDDQALLE
RTRELIASPP DMVVITTGIG MRGWFEAATA AGIADELRTA LAGATILARG PKGRGAIQQA
GLSAAWVSES ETAAEVADHL RTLDVTGQRV AVQHHGSGAD GLDELLDEMG AEVVSLTVYR
WGPPRDAEAV RRSVHDAATG ELDAVVSTAA PGAARWLEVA DEEGVLDGIR ERAKSGDLVL
AVVGPVNAGP YEELDIPVLQ PERMRLGSMV KAIVQHYAEQ RRG
//
