ID A0A022KWP1_9MICO Unreviewed; 333 AA.
AC A0A022KWP1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:EYT49328.1};
GN ORFNames=D641_0107830 {ECO:0000313|EMBL:EYT49328.1};
OS Brachybacterium muris UCD-AY4.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=1249481 {ECO:0000313|EMBL:EYT49328.1, ECO:0000313|Proteomes:UP000019754};
RN [1] {ECO:0000313|EMBL:EYT49328.1, ECO:0000313|Proteomes:UP000019754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCD-AY4 {ECO:0000313|EMBL:EYT49328.1,
RC ECO:0000313|Proteomes:UP000019754};
RX PubMed=23516213;
RA Lo J.R., Lang J.M., Darling A.E., Eisen J.A., Coil D.A.;
RT "Draft genome sequence of an Actinobacterium, Brachybacterium muris strain
RT UCD-AY4.";
RL Genome Announc. 1:E0008613-E0008613(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT49328.1}.
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DR EMBL; AORC01000009; EYT49328.1; -; Genomic_DNA.
DR RefSeq; WP_017823099.1; NZ_AORC01000009.1.
DR AlphaFoldDB; A0A022KWP1; -.
DR STRING; 1249481.D641_0107830; -.
DR HOGENOM; CLU_037628_6_1_11; -.
DR OrthoDB; 3227375at2; -.
DR Proteomes; UP000019754; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000019754};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 333 AA; 35242 MW; 22FCE6E5DB2D6965 CRC64;
MPRSRPTLAD VARAAGVSSA TASMALNDRP GVRHETRLAV LAAARTVGYR RAGRGTSGLI
GVLPTDLGNP YHTDVIAGIE EQAERQGTGV VIAHGRRDSA HLERQLQRLL DLGVDGVIAV
TTWLSPTALE AAAALLPVVV IGRMQDAVPG TDTVRNDDEA GAALAVRHLV ERGHRHLVHV
TLSTRPGPAS RRAGFLAEAE RLGLRDRARV IGPDSPAEGM ELVLRALRRG DPDAPTAVFA
ANDIAAVSVL HRAADRGIRV PEQLSVVGYD SSTVALTVRP HLTSVNQPRS EMGRLAAQML
QERWRGRAHD AVSVVAPVLR VRGSTGTGPA LLS
//
