GenomeNet

Database: UniProt
Entry: A0A022L968_9ACTN
LinkDB: A0A022L968_9ACTN
Original site: A0A022L968_9ACTN 
ID   A0A022L968_9ACTN        Unreviewed;      1063 AA.
AC   A0A022L968;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   05-JUN-2019, entry version 23.
DE   SubName: Full=Carbamoyl-phosphate synthase large subunit {ECO:0000313|EMBL:EYT58662.1};
GN   ORFNames=H483_0114470 {ECO:0000313|EMBL:EYT58662.1};
OS   Dietzia sp. UCD-THP.
OC   Bacteria; Actinobacteria; Corynebacteriales; Dietziaceae; Dietzia.
OX   NCBI_TaxID=1292020 {ECO:0000313|EMBL:EYT58662.1, ECO:0000313|Proteomes:UP000019757};
RN   [1] {ECO:0000313|EMBL:EYT58662.1, ECO:0000313|Proteomes:UP000019757}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCD-THP {ECO:0000313|EMBL:EYT58662.1,
RC   ECO:0000313|Proteomes:UP000019757};
RX   PubMed=23661480;
RA   Diep A.L., Lang J.M., Darling A.E., Eisen J.A., Coil D.A.;
RT   "Draft Genome Sequence of Dietzia sp. Strain UCD-THP (Phylum
RT   Actinobacteria).";
RL   Genome Announc. 1:E00197-13(2013).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EYT58662.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AOSR01000050; EYT58662.1; -; Genomic_DNA.
DR   RefSeq; WP_017838055.1; NZ_KB714656.1.
DR   STRING; 1292020.H483_0114470; -.
DR   EnsemblBacteria; EYT58662; EYT58662; H483_0114470.
DR   OrthoDB; 886663at2; -.
DR   Proteomes; UP000019757; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   InterPro; IPR034733; AcCoA_carboxyl.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR005481; BC-like_N.
DR   InterPro; IPR001882; Biotin_BS.
DR   InterPro; IPR011764; Biotin_carboxylation_dom.
DR   InterPro; IPR005482; Biotin_COase_C.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR011763; COA_CT_C.
DR   InterPro; IPR011762; COA_CT_N.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   InterPro; IPR011054; Rudment_hybrid_motif.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF02785; Biotin_carb_C; 1.
DR   Pfam; PF00289; Biotin_carb_N; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF01039; Carboxyl_trans; 1.
DR   Pfam; PF02786; CPSase_L_D2; 1.
DR   SMART; SM00878; Biotin_carb_C; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   SUPFAM; SSF51246; SSF51246; 1.
DR   SUPFAM; SSF52096; SSF52096; 2.
DR   SUPFAM; SSF52440; SSF52440; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS50979; BC; 1.
DR   PROSITE; PS00188; BIOTIN; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS50989; COA_CT_CTER; 1.
DR   PROSITE; PS50980; COA_CT_NTER; 1.
DR   PROSITE; PS00867; CPSASE_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW   Complete proteome {ECO:0000313|Proteomes:UP000019757};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT   DOMAIN        1    452       Biotin carboxylation.
FT                                {ECO:0000259|PROSITE:PS50979}.
FT   DOMAIN      119    318       ATP-grasp. {ECO:0000259|PROSITE:PS50975}.
FT   DOMAIN      456    532       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
FT   DOMAIN      549    816       CoA carboxyltransferase N-terminal.
FT                                {ECO:0000259|PROSITE:PS50980}.
FT   DOMAIN      808   1049       CoA carboxyltransferase C-terminal.
FT                                {ECO:0000259|PROSITE:PS50989}.
SQ   SEQUENCE   1063 AA;  111061 MW;  5EE5F3352659BDB0 CRC64;
     MPESVFVANR GEIALRIVRA ASEIGLDVVV AVTRAEVDSL AARVATGVHV LPGEGAGAYL
     DAESLVAGAT EHGCTLLHPG YGFLSESPVL ARACAAAGVT FVGPDASLLE LFGDKGSARA
     AAHAAGVPVL PATDVGVTRD QVEAFAREQE PAGVMVKAAA GGGGRGMRAV PAGEPLADAW
     ERARSEAERS VGSGALFAEL YVARARHIEV QVVADGDGGV THLGDRDCTL QRRFQKFVEV
     APAPDLPDEV RADLHAAALR LLAGRGYRGL ATVEFLVDAD HPTRWWFIEV NPRLQVEHPV
     TELVTGVDLV LAQLRLASGG TLADLGLSSP PRVTGAAVEV RVAAERTGIS GEALPAQGVV
     SGLALPAGPG VRVDTHLVEG TRVDGSFDSL VAKIVTHSHG GHAGAIAKAR QAVDECAIGG
     LETTLPVLSE VLGHDDVATW SVTTQWFASA DLSRAAVPAH VVDGEVLAEM GGTVVAVLVE
     EGQDVAAGTP LLVVEAMKME HLLPAPVSGE VAAIRVAAGA TVVAGDLLVR LLPSADQSAT
     GAVEDGPDLD SDRPDLARVL ERRDRRMDDA RPEAVARRHA RGQRTARENI ADLVDEGSFV
     EYGGFAVAAQ RARRTEEDLI ANTPADGIIT GIGRITAAPA EDTRCAVLAY DYTVLAGTQG
     YLNHKKTDRM LELAEQQRLP VILFAEGGGG RPGDTDTTVV SGLDVPTFAT MGRLSGQVPT
     IGIAAGRCFA GNAALLGCCD VVIATRDSTI GMGGPAMIEG GGLGLYSPDE VGPIDVQSGN
     GVVDVVVADE AEAVAVARRY LGYFQGVQPE WAAADQRTLR HVVPENRVRA YDIHAAIDAL
     ADEGSVLELR AGFAPGIVTA LVRIEGRPMG LVANNPRHLG GAIDTPAADK LARFLQLCDA
     HGLPVVSLCD TPGFMVGPDH ERTATVRHFA RLFVIGAHLR VPIVTVVLRK AYGLGAQAMA
     AGSFHRPAAT LAWPTGEVGG MGLEGAVRLG FRRELEAVAD PTERRELEDR LLADLYERGR
     AVNAAAVVEL DDVIDPADTR RWILTAMATA TPVDGPTRYI DTW
//
DBGET integrated database retrieval system