ID   A0A022LRJ8_9ACTN        Unreviewed;       394 AA.
AC   A0A022LRJ8;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Fatty acid desaturase {ECO:0000313|EMBL:EYT64174.1};
GN   ORFNames=H483_0105910 {ECO:0000313|EMBL:EYT64174.1};
OS   Dietzia sp. UCD-THP.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Dietziaceae;
OC   Dietzia.
OX   NCBI_TaxID=1292020 {ECO:0000313|EMBL:EYT64174.1, ECO:0000313|Proteomes:UP000019757};
RN   [1] {ECO:0000313|EMBL:EYT64174.1, ECO:0000313|Proteomes:UP000019757}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCD-THP {ECO:0000313|EMBL:EYT64174.1,
RC   ECO:0000313|Proteomes:UP000019757};
RX   PubMed=23661480;
RA   Diep A.L., Lang J.M., Darling A.E., Eisen J.A., Coil D.A.;
RT   "Draft Genome Sequence of Dietzia sp. Strain UCD-THP (Phylum
RT   Actinobacteria).";
RL   Genome Announc. 1:E00197-E00113(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYT64174.1}.
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DR   EMBL; AOSR01000016; EYT64174.1; -; Genomic_DNA.
DR   RefSeq; WP_017836680.1; NZ_KB714632.1.
DR   AlphaFoldDB; A0A022LRJ8; -.
DR   eggNOG; COG3239; Bacteria.
DR   HOGENOM; CLU_045383_0_0_11; -.
DR   Proteomes; UP000019757; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:UniProt.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR   CDD; cd03506; Delta6-FADS-like; 1.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR   PANTHER; PTHR19353:SF84; NADPH-DEPENDENT STEAROYL-COA 9-DESATURASE; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          86..352
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   394 AA;  44739 MW;  FFC8AADB7F469130 CRC64;
     MTLLQLPTIR STKPKTSKPK ATAPEPVVLS AESVEIIGRE LDAIRDRVVA DLGTADRDYI
     LRVVRMQRRL ELTGRALMFL GFLPPAWLAG VAALSASKIL DNMEIGHNVM HGQYDWMRDD
     MLHSSSFEWD NVCPSDQWRH SHNYMHHTHT NILDLDRDIG YGILRMEYEQ KWTPLRLGNP
     LYAFGLMMAF EWGVMLHDLE YDNVLKGKRK WSDVKGLLAG WWGKMRGQVA KDYIVHPALT
     GPLFPLTFAG NLTANLVRNV WAFSVIFCGH FPSGAQVFTQ EETAEETRGE WYVRQMLGSA
     NISGSPFMHL ATGNLSHQIE HHLFPDLPAH RYPEIAEEVR AICEEHGLPY TTGPLWKQVA
     NVWVKMFRLA LPLPPTPADT PAVLIERRKV TPTA
//