ID A0A022MCI1_9ACTN Unreviewed; 399 AA.
AC A0A022MCI1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Colicin V synthesis protein {ECO:0000313|EMBL:EYT80236.1};
GN ORFNames=CF54_26520 {ECO:0000313|EMBL:EYT80236.1};
OS Streptomyces sp. Tu 6176.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT80236.1, ECO:0000313|Proteomes:UP000020060};
RN [1] {ECO:0000313|EMBL:EYT80236.1, ECO:0000313|Proteomes:UP000020060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT80236.1,
RC ECO:0000313|Proteomes:UP000020060};
RA Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT cytotoxic benzoxazol nataxazol.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT80236.1}.
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DR EMBL; JFJQ01000853; EYT80236.1; -; Genomic_DNA.
DR RefSeq; WP_037894248.1; NZ_KK106991.1.
DR AlphaFoldDB; A0A022MCI1; -.
DR HOGENOM; CLU_043139_0_0_11; -.
DR OrthoDB; 9766361at2; -.
DR Proteomes; UP000020060; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR GO; GO:0009403; P:toxin biosynthetic process; IEA:InterPro.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR003825; Colicin-V_CvpA.
DR InterPro; IPR047680; MarP-like.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; NF033740; MarP_fam_protase; 1.
DR PANTHER; PTHR43019; SERINE ENDOPROTEASE DEGS; 1.
DR PANTHER; PTHR43019:SF36; SERINE PROTEASE RV3671C; 1.
DR Pfam; PF02674; Colicin_V; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..21
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 399 AA; 42228 MW; DA91C2B9755E6CD1 CRC64;
MNVLDILLLV AAVWFAVVGY RQGFVVGILS VIGFLGGGLV AVYALPVIWD ALTDHTPVST
TAAVVAVIVV IICASVGQAL TTHLGNKLRV HITWSPARAL DATGGAMVNV LAMLLVAWLI
GSALGGTTIP TLGKEVRTSQ VLLGVSRVMP QQADTWFADF TSVLAQNGFP QVFSPFTDEP
ITDVQPPDPA LRDSAVARSA KRSVVKVVGT ASSCGKVLEG SGFVFGPRRV MTNAHVVGGV
DEPTVQIGGE GRKYDAKVVL YDWHRDIAVL DVPDLKAPVL RFSDSVAHSK DSAIVAGFPE
NGAYDVRSAR VRGRITANGP DIYHRGTVRR DVYSLYATVR QGNSGGPLLT TDGEVYGVVF
AKSLDDAETG YALTAGEIEQ DIAKGRTAVQ QVDTDRCAM
//
