ID A0A022MDR5_9ACTN Unreviewed; 397 AA.
AC A0A022MDR5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Serine protease {ECO:0000313|EMBL:EYT80702.1};
GN ORFNames=CF54_23935 {ECO:0000313|EMBL:EYT80702.1};
OS Streptomyces sp. Tu 6176.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT80702.1, ECO:0000313|Proteomes:UP000020060};
RN [1] {ECO:0000313|EMBL:EYT80702.1, ECO:0000313|Proteomes:UP000020060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT80702.1,
RC ECO:0000313|Proteomes:UP000020060};
RA Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT cytotoxic benzoxazol nataxazol.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT80702.1}.
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DR EMBL; JFJQ01000758; EYT80702.1; -; Genomic_DNA.
DR RefSeq; WP_037893478.1; NZ_KK106990.1.
DR AlphaFoldDB; A0A022MDR5; -.
DR MEROPS; S01.513; -.
DR HOGENOM; CLU_043139_0_0_11; -.
DR OrthoDB; 9766361at2; -.
DR Proteomes; UP000020060; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR GO; GO:0009403; P:toxin biosynthetic process; IEA:InterPro.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR003825; Colicin-V_CvpA.
DR InterPro; IPR047680; MarP-like.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; NF033740; MarP_fam_protase; 1.
DR PANTHER; PTHR43019; SERINE ENDOPROTEASE DEGS; 1.
DR PANTHER; PTHR43019:SF36; SERINE PROTEASE RV3671C; 1.
DR Pfam; PF02674; Colicin_V; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EYT80702.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000313|EMBL:EYT80702.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 397 AA; 40336 MW; 2D14E24A0F37AE9E CRC64;
MDLLDLVLLL VVVLYAASGY RRGLVAGCVS LAGFVGGAAV GVWVLPWVMD LVTRGSTAAT
VTAVVTVLVP AVAGHELAGR LALRLRSRLE GAGGGSLRAA DGIGGAAANA VAVLIVAWVA
ASVLGASSSP VVTTAIRDSK LLGAVQDAMP DTTPAWFSRA TSALTEAGFP QVFNPFENEP
AAGVARPSGD SVTASATNAA RLSTVKIEGS SGDQGREGSG FVFARQRVMT NAHVVAGIDA
PYVQIGGVGH TYAARVVLFD PDRDVAVLYV PGLRAPVLRF DGTAGRGDAA VVAGYPQDGG
LDLQAATVAN RIRATGRNIY NSATVTREIY SIRSTVRPGN SGGPLLTTDG RVYGMVFARS
TSDAETGYAL TAAEVAADAR RAAAATTAVD TGRLVAA
//
