ID A0A022MEK3_9ACTN Unreviewed; 524 AA.
AC A0A022MEK3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Tryptophan halogenase {ECO:0000313|EMBL:EYT79768.1};
GN ORFNames=CF54_29390 {ECO:0000313|EMBL:EYT79768.1};
OS Streptomyces sp. Tu 6176.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT79768.1, ECO:0000313|Proteomes:UP000020060};
RN [1] {ECO:0000313|EMBL:EYT79768.1, ECO:0000313|Proteomes:UP000020060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT79768.1,
RC ECO:0000313|Proteomes:UP000020060};
RA Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT cytotoxic benzoxazol nataxazol.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the flavin-dependent halogenase family.
CC Bacterial tryptophan halogenase subfamily.
CC {ECO:0000256|ARBA:ARBA00038396}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT79768.1}.
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DR EMBL; JFJQ01000936; EYT79768.1; -; Genomic_DNA.
DR RefSeq; WP_051576470.1; NZ_KK106992.1.
DR AlphaFoldDB; A0A022MEK3; -.
DR HOGENOM; CLU_024648_4_0_11; -.
DR OrthoDB; 103324at2; -.
DR Proteomes; UP000020060; Unassembled WGS sequence.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR Gene3D; 3.30.9.100; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006905; Flavin_halogenase.
DR PANTHER; PTHR43747:SF1; FAD-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR Pfam; PF04820; Trp_halogenase; 2.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
SQ SEQUENCE 524 AA; 57102 MW; AAE7C92DD1A1211B CRC64;
MSTPEHATGT TPAGPAGSYD VVVVGGGPGG STTAALVAMA GHRVLLLEKE SFPRHQIGES
LLPATIHGVC RFLGVTEELE KAGFMPKRGG TFRWGSNPEP WNFLFAYSPL MSGPTSTAYQ
VERMKFDKIL LDNARRLGVE VRERCTAVAT LSEGERITGL RWTDEDGRTH ETAARYVVDA
SGSNSKLART VGKRNYSDFF RNVALYGYYE GGKRLPGPDA GNILCCAWDD GWFWYIPLTD
TLTSVGAVVN RSQVGTLSRD PEGAMAQFIE QAPMIKEFLQ DAERVTEGPY GELRVRKDYS
YAMERFWQPG MVLVGDAACF VDPVFSTGVH LATYGGLLAA RSINSALDGE LDEERAFGEF
ERRYRREYGV FYEFLLAFYD MQHNEESYFW QARKVSRAEA TDLRAFVELV GGVSSGESAL
TDLETLKERF GGSSRELADA VTRTGPAQTE SGERMGELFG TQVVTEVMQG MNEVQARASM
GGATTLEKPL FEDGLVASND GLGWAVPVTA DAAAAVSAQE GPAA
//
