ID   A0A022MME6_9ACTN        Unreviewed;       794 AA.
AC   A0A022MME6;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=PAS/PAC sensor protein {ECO:0000313|EMBL:EYT82468.1};
GN   ORFNames=CF54_13095 {ECO:0000313|EMBL:EYT82468.1};
OS   Streptomyces sp. Tu 6176.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT82468.1, ECO:0000313|Proteomes:UP000020060};
RN   [1] {ECO:0000313|EMBL:EYT82468.1, ECO:0000313|Proteomes:UP000020060}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT82468.1,
RC   ECO:0000313|Proteomes:UP000020060};
RA   Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT   "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT   cytotoxic benzoxazol nataxazol.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYT82468.1}.
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DR   EMBL; JFJQ01000404; EYT82468.1; -; Genomic_DNA.
DR   RefSeq; WP_037890270.1; NZ_KK106988.1.
DR   AlphaFoldDB; A0A022MME6; -.
DR   HOGENOM; CLU_000445_43_3_11; -.
DR   OrthoDB; 118142at2; -.
DR   Proteomes; UP000020060; Unassembled WGS sequence.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
FT   DOMAIN          16..42
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          182..237
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   REGION          301..324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   794 AA;  84562 MW;  0811CD092564DA16 CRC64;
     MSPVYPFDDA ATARAVVDER GILVEWNEGA RRLLGWAPDD VLAAPAAGLL ADSSGAAPPD
     GGRWSGILTL RHRDGHTVSV WVLAHRRRPQ EGGGWLAVTP LEDAVPGDPD DDPLTEAGLV
     QSPCAVALYD DRLRLRAVND AMAEVLGVSG DRLRGLRHSE IGAGPQSADI ERRMLQVLDT
     GRPHDVRAYV PVGGDGRTSA WMARLSPITD GAGRVRGVCV AAHDFTEQYR ARERLQLVNE
     ASVRIGTTLD VTRTAQELAD VCVPALADFV SVDLVDPPEH GGELPIGTLS VPVELRRAAH
     RSVTPGDPEA VTPPGGTEVY PAASPQGASL LSGHAIVVSE NSGDLAKWLA WSPARSLRVG
     RLGVHSTMSV PIRARGMTLG VAVFTRFAQP ARFLPDDVLL AEEVTARAAV CIDNARRYSR
     ERETALALQR SLLPRTLART AAVAAASRYL PAARAGVGGD WFDVIPLSGM RVALVVGDVI
     GHGVGASATM GRLRTAVRTL ADIDLAPDEL LTHLDDVVAR MSAEAGDEAD GRPGEVGATC
     LYAVYDPVSR RCTLARAGHP APVLVPPDGP PRRIDLPPGP PLGLGGLPFE SAELDLDEGS
     VLAFYTDGLV DSRERNVEAG QLLLRETLAE GGESLEESCD RVLHALLPAG SPADDVALLL
     ARTRGLPPSQ VATWDIPADP SLVAPVRKQV VDQLGTWGLD LVAFTAELVV SELVTNAIRY
     GTPPIRLRLI HDDTHLICEV SDTSNTAPHL RRAKTWDEGG RGLLLVAQLT QRWGSRHTTE
     GKTIWAELNL LGEE
//