ID A0A022MN35_9ACTN Unreviewed; 501 AA.
AC A0A022MN35;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=AMP-dependent synthetase {ECO:0000313|EMBL:EYT82763.1};
GN ORFNames=CF54_11360 {ECO:0000313|EMBL:EYT82763.1};
OS Streptomyces sp. Tu 6176.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT82763.1, ECO:0000313|Proteomes:UP000020060};
RN [1] {ECO:0000313|EMBL:EYT82763.1, ECO:0000313|Proteomes:UP000020060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT82763.1,
RC ECO:0000313|Proteomes:UP000020060};
RA Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT cytotoxic benzoxazol nataxazol.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT82763.1}.
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DR EMBL; JFJQ01000345; EYT82763.1; -; Genomic_DNA.
DR RefSeq; WP_037889889.1; NZ_KK106988.1.
DR AlphaFoldDB; A0A022MN35; -.
DR HOGENOM; CLU_000022_59_10_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000020060; Unassembled WGS sequence.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
FT DOMAIN 11..365
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 415..488
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 501 AA; 52871 MW; 42F15F6918908D62 CRC64;
MATLSVAAIL AENARRRPHR TALVEGDLRL SFAQVWQRAR AQAGALAGLG IRPGDRVALM
APNTAEFPQA YYAIAAAGAV VVPVHLLLSA AEVEHVLRDS GAALLLCHPA QADTGTAAAR
ATGVRVVTLG AELETLAAGA EPLPSYVTRA ADDPAVVFYT SGTTGVPKGA VLSHFNLVMN
ATVNAFDAND IRPDDIALGA LPLFHAFGQT VSMNSTWRAG ATLVLLPRFD ASRAIELMVK
EGVNTFHGVP TMFVSLAAAA PGADVLPDLR LCVSGGASLP VAVLERFEAA FGARIHEGYG
LSETSPAAAV NQPVFGTRPG SIGHPLWGVD VEIARAETED RVELLPPGEV GEVVVRGHNV
FSGYLGRPEA TAEALVDGWF RTGDLGTKDD EGFLRIVDRK KDVIIRGGYN VYPREVEEVL
LRHPAVAQAA VIGLPDDLHG EEVCAVVVPA PGAGPDAAAV TAWAKEHLGR HKYPRRVEFT
DALPLGPSMK VLKRELRARY A
//
