ID A0A022Q1Q1_ERYGU Unreviewed; 259 AA.
AC A0A022Q1Q1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic {ECO:0000256|HAMAP-Rule:MF_03192};
DE EC=2.1.1.329 {ECO:0000256|HAMAP-Rule:MF_03192};
DE AltName: Full=Demethylphylloquinone methyltransferase {ECO:0000256|HAMAP-Rule:MF_03192};
DE AltName: Full=Menaquinone biosynthesis methyltransferase ubiE-like protein {ECO:0000256|HAMAP-Rule:MF_03192};
GN Name=MENG {ECO:0000256|HAMAP-Rule:MF_03192};
GN ORFNames=MIMGU_mgv1a012189mg {ECO:0000313|EMBL:EYU22512.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU22512.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU22512.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- FUNCTION: Involved in the biosynthesis of phylloquinone (vitamin K1).
CC Methyltransferase required for the conversion of 2-phytyl-1,4-beta-
CC naphthoquinol to phylloquinol. {ECO:0000256|HAMAP-Rule:MF_03192}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=demethylphylloquinol + S-adenosyl-L-methionine = H(+) +
CC phylloquinol + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:40551,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:28433, ChEBI:CHEBI:57856,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:87844; EC=2.1.1.329;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_03192};
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000256|HAMAP-
CC Rule:MF_03192}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. MenG/UbiE family. {ECO:0000256|HAMAP-Rule:MF_03192}.
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DR EMBL; KI632201; EYU22512.1; -; Genomic_DNA.
DR RefSeq; XP_012855358.1; XM_012999904.1.
DR AlphaFoldDB; A0A022Q1Q1; -.
DR STRING; 4155.A0A022Q1Q1; -.
DR GeneID; 105974760; -.
DR KEGG; egt:105974760; -.
DR eggNOG; KOG1540; Eukaryota.
DR OMA; RYYWDTI; -.
DR OrthoDB; 46567at2759; -.
DR PhylomeDB; A0A022Q1Q1; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0052624; F:2-phytyl-1,4-naphthoquinone methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008168; F:methyltransferase activity; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_01982; MenG_phylloquinone_subfam; 1.
DR HAMAP; MF_01813; MenG_UbiE_methyltr; 1.
DR InterPro; IPR032904; MenG.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004033; UbiE/COQ5_MeTrFase.
DR InterPro; IPR023576; UbiE/COQ5_MeTrFase_CS.
DR NCBIfam; TIGR01934; MenG_MenH_UbiE; 1.
DR PANTHER; PTHR43591; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43591:SF106; METHYLTRANSFERASE-LIKE PROTEIN 27; 1.
DR Pfam; PF01209; Ubie_methyltran; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51608; SAM_MT_UBIE; 1.
DR PROSITE; PS01183; UBIE_1; 1.
PE 3: Inferred from homology;
KW Chloroplast {ECO:0000256|HAMAP-Rule:MF_03192};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|HAMAP-
KW Rule:MF_03192}; Plastid {ECO:0000256|HAMAP-Rule:MF_03192};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691, ECO:0000256|HAMAP-
KW Rule:MF_03192};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_03192}.
SQ SEQUENCE 259 AA; 28564 MW; A6223A2AD94B9EB9 CRC64;
MATLQLNLHS VTGGQRRPAC RSVITPIRCA AERQALFNRI APVYDNLNDL LSLGRHRVWK
RMAVSWSGAK EGDTVLDVCC GSGDLAFLLS EKVGINGKVI ALDFSKEQLK IAASRQSERS
KSCYKNIEWI EGDAMDLPFS GSSFDAATIG YGLRNVVHRK KALEEMCRVL KPGSKVSVLD
FNKSTSPLTS SLQDWMIDNV VVPVANGYGL ASEYRYLKNS IKEYLSGNEL EKLAFEAGFS
EGKHYEIDAG FMGNLVATR
//
