ID A0A022QD13_ERYGU Unreviewed; 470 AA.
AC A0A022QD13;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=CNNM transmembrane domain-containing protein {ECO:0000259|PROSITE:PS51846};
GN ORFNames=MIMGU_mgv1a026448mg {ECO:0000313|EMBL:EYU25153.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU25153.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU25153.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI632098; EYU25153.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A022QD13; -.
DR STRING; 4155.A0A022QD13; -.
DR eggNOG; KOG2118; Eukaryota.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030026; P:intracellular manganese ion homeostasis; IBA:GO_Central.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064:SF36; DOMAIN-CONTAINING PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..192
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT REGION 411..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 470 AA; 51353 MW; A80B713B307B12B9 CRC64;
MAANDVPCCE TMFWVYLVIC VSLVCFAGVM SGLTLGLMSL SLVDLEVLIT AGKPDDRKNA
EKILPIVKNQ HLLLCTLLIW NALAMEALPI FVDALLPAWG AVLISVTLIL VFGEIIPQAV
CSRYGLNVGA KLSVVVRLLV IIVFPLSYPI SKLLDLLLGK GHSALLRRAE LKTLVGMHGN
EAGKGGELTH DETTIISGAL DLSEKTAKDA MTPLSSVFSL DLNAKLDNDT MSLIISKGHS
RVPIYSGTAS NIVGLVLVKN LIKCSPQDET LIRNLTIRRI PRFSECLPLY DILNQFQKGQ
SHMAVVIKSN SLVKNNTDIE SDALEINVDS SSTNRQTDRN SSIHYDSDEE VIGIITMEDV
LEELIQGQIF DETDEYVDIH NRIKINLSPT LKLSSKSLSP YSSIHQTPIS CHQTATTRSP
LSPYTQSPIF RPSLSNSTGN SASASPVGNV GPIYGSPSNY QVQFWKEEKY
//
