ID A0A022QFB5_ERYGU Unreviewed; 585 AA.
AC A0A022QFB5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=MIMGU_mgv1a003441mg {ECO:0000313|EMBL:EYU26289.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU26289.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU26289.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr
CC protein kinase family. MAP kinase subfamily.
CC {ECO:0000256|ARBA:ARBA00008832}.
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DR EMBL; KI631699; EYU26289.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A022QFB5; -.
DR STRING; 4155.A0A022QFB5; -.
DR eggNOG; KOG0660; Eukaryota.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004707; F:MAP kinase activity; IBA:GO_Central.
DR GO; GO:0035556; P:intracellular signal transduction; IBA:GO_Central.
DR CDD; cd07859; STKc_TDY_MAPK; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR003527; MAP_kinase_CS.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR PANTHER; PTHR24055; MITOGEN-ACTIVATED PROTEIN KINASE; 1.
DR PANTHER; PTHR24055:SF200; MITOGEN-ACTIVATED PROTEIN KINASE 19; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS01351; MAPK; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748}.
FT DOMAIN 36..327
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 409..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..441
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 66
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 585 AA; 66218 MW; 819AC603A91C6F5D CRC64;
MLLLKENLRF SDRKLTILQI PKEVEFFTEY GDANRYKILE IVGKGSYGVV CAAIDTHTGE
KVAIKKIKDI FEHLSDATRI LREIKLLRLL RHPDIVEIKR IMMPPSRRDF RDIYVVFELM
ESDLHQVIKA NDDLTHEHHR FFLYQMLRAM KFMHTANVFH RDLKPKNILA NANCKLKICD
LGLARVAFND TPTTAFWTDY VATRWYRAPE LCGSFFSKYT PAIDIWSIGC IFAEVVTGKP
LFPGKSVVHQ LDLITNLLGT PSIDTISGVR NEKARKYLMD MRKKRTVPFA EKFPSVDPSA
LKLLQRLLAF DPKDRPSAEE ALADPYFKGL AKIEREPSCQ PISKLEFEFE LRRVTKDDIR
ELIFREILEY HPQLLKDYME RNEGTSFLYP SAIGHFKKQF AYLEENAGKS GPVIPPERKH
VSLPRSSISS STNPSKAQTN LSSFDNRETL AEASTGLRFS GLNSGDNIAK VPLPPPPRVP
NAKPGRVVGP VLPYENVRDA NDKSRNGTSV DFDWKRQSQT AESYPVVNSK PNFQSQPKVG
IMNSSQQIAV DAKLLQTRSH FVAAGAAAVA VAAHREVGAV QLGFT
//
