ID A0A022QFB8_ERYGU Unreviewed; 669 AA.
AC A0A022QFB8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=NAD(P)-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MIMGU_mgv1a002474mg {ECO:0000313|EMBL:EYU26294.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU26294.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU26294.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR EMBL; KI631699; EYU26294.1; -; Genomic_DNA.
DR RefSeq; XP_012850628.1; XM_012995174.1.
DR AlphaFoldDB; A0A022QFB8; -.
DR STRING; 4155.A0A022QFB8; -.
DR GeneID; 105970366; -.
DR KEGG; egt:105970366; -.
DR eggNOG; KOG0747; Eukaryota.
DR OMA; NTLQCRI; -.
DR OrthoDB; 5486426at2759; -.
DR PhylomeDB; A0A022QFB8; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:InterPro.
DR GO; GO:0050377; F:UDP-glucose 4,6-dehydratase activity; IBA:GO_Central.
DR GO; GO:0010280; F:UDP-L-rhamnose synthase activity; IBA:GO_Central.
DR GO; GO:0010315; P:auxin export across the plasma membrane; IBA:GO_Central.
DR GO; GO:0051555; P:flavonol biosynthetic process; IBA:GO_Central.
DR GO; GO:0010253; P:UDP-rhamnose biosynthetic process; IBA:GO_Central.
DR CDD; cd05246; dTDP_GD_SDR_e; 1.
DR CDD; cd05254; dTDP_HR_like_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR005888; dTDP_Gluc_deHydtase.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR029903; RmlD-like-bd.
DR NCBIfam; TIGR01181; dTDP_gluc_dehyt; 1.
DR PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR Pfam; PF16363; GDP_Man_Dehyd; 1.
DR Pfam; PF04321; RmlD_sub_bind; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748}.
FT DOMAIN 10..315
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF16363"
FT DOMAIN 383..552
FT /note="RmlD-like substrate binding"
FT /evidence="ECO:0000259|Pfam:PF04321"
SQ SEQUENCE 669 AA; 75185 MW; AD96F9440BB22521 CRC64;
MSTFTPKNIL ITGAAGFIAS HVANRLIRNY PEYKIVVLDK LDYCSNLKNL LPSKASANFK
FVKGDIGSAD LVNYLLITEN IDTIMHFAAQ THVDNSFGNS FEFTKNNIYG THVLLEACKV
TGQIRRFIHV STDEVYGETE EDAVVGNHEA SQLLPTNPYS ATKAGAEMLV MAYGRSYGLP
VITTRGNNVY GPNQFPEKLI PKFILLAMAG KTLPIHGDGS NVRSYLYCED VAEAFEVVLH
KGEVGHVYNI GTKKERRVID VAEDICKLFN MDPEKSIKFV ENRPFNDQRY FLDDQKLKNI
GWSEKTAWEE GLKKTIEWYR SNPEWWGDVS GALLPHPRML MMPGGIERHF DGAEKYESGK
SEFTGESKPN PEISPSPQKP ALKFLIYGKT GWIGGLLGKL CEKQGIAYEY GKGRLQDRST
LLADIKSVKP THVFNAAGVT GRPNVDWCES HKTETIRTNV VGTLTLADVC REQGLLMMNY
ATGCIFEYDA AHPEGSGIGF KEEDTPNFHG SFYSKTKAMV EELLKEYDNV CTLRVRMPIS
SDLSNPRNFI TKISKYNKVV NIPNSMTVLD ELLPISIEMA KRNLRGIYNF TNPGVVSHNE
ILEMYKQYID PDFKYSNFTL EEQAKVIVAA RSNNEMDASK LKKEFPELLS IKDSLIKIVF
EPNRKTPAA
//
