ID A0A022QIR8_ERYGU Unreviewed; 1649 AA.
AC A0A022QIR8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Non-specific serine/threonine protein kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MIMGU_mgv1a000137mg {ECO:0000313|EMBL:EYU27876.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU27876.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU27876.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
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DR EMBL; KI631456; EYU27876.1; -; Genomic_DNA.
DR STRING; 4155.A0A022QIR8; -.
DR eggNOG; ENOG502QSUU; Eukaryota.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0048544; P:recognition of pollen; IEA:InterPro.
DR CDD; cd00028; B_lectin; 2.
DR CDD; cd01098; PAN_AP_plant; 2.
DR CDD; cd14066; STKc_IRAK; 2.
DR Gene3D; 2.90.10.10; Bulb-type lectin domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR001480; Bulb-type_lectin_dom.
DR InterPro; IPR036426; Bulb-type_lectin_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR003609; Pan_app.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR000858; S_locus_glycoprot_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR32444; BULB-TYPE LECTIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR32444:SF150; RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE; 1.
DR Pfam; PF01453; B_lectin; 2.
DR Pfam; PF08276; PAN_2; 2.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 2.
DR Pfam; PF00954; S_locus_glycop; 2.
DR SMART; SM00108; B_lectin; 2.
DR SMART; SM00473; PAN_AP; 2.
DR SMART; SM00220; S_TKc; 2.
DR SUPFAM; SSF51110; alpha-D-mannose-specific plant lectins; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
DR PROSITE; PS50927; BULB_LECTIN; 2.
DR PROSITE; PS50948; PAN; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 2.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1649
FT /note="Non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001504289"
FT TRANSMEM 433..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1252..1276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..147
FT /note="Bulb-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50927"
FT DOMAIN 338..421
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 513..801
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 838..963
FT /note="Bulb-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50927"
FT DOMAIN 1155..1243
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 1334..1620
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 541
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1649 AA; 185030 MW; 56FF73F3FD389652 CRC64;
MTRNTKPAIF FVIICVPFLG FSLETDTISS GLFIKDPDTI ISPGHVFKLG FFTPNTNSTN
RYLGVFYNVS EKTVIWVANR DNPLRDSSGS VTMSQNGNLV LLNGQNQTIW STNSTATSAN
TTTAHITDSG NLVLRDNATG AAIWESFSYP TNTYVPTMNI TDNINTGKKV VLSSWANDDS
NPETGSFTSG VVALNIPQIL IWKNGRRHWR SGPWNGRILI GVRDMYSALL STASISNDSS
GTFYFTFPQW RVLSKVELNS SGSLALTLWS EPKQSWDALW LAPETGCDIY GTCGPFGSCN
NQGSPVCSCL KGFEPANTEE WRRGNWTSGC RRINQLQCDI QNNGKSGDGF FMEQFMKVPD
FADQFSAGDK DECRRRCLRN CSCIAYAHDA NIGCMFWSNT TALIDVQKFT GVGVDLYLRL
SALDLDNDKD KKLYIIIPIV AGFVCISVLI FIGWCWLVKR KGGKTKEKRI FEAEQTLSSD
STAIVLKDES GKINIEELPL FTFETLANAT DQFHENNLLG RGGFGHVYKG NLGNGKEIAV
KRLSAASGQG MEEFMNEVIV ISKLQHRNLV RLHGCCVEKE EKMLVYEYMP NKSLDVCLFD
STHPSRKDLD WKKRSSIIEG VGRGLIYLHR DSRLRIIHRD LKPSNVLLDE NWNPKISDFG
MARIFGGNQD HGNTARVVGT YGYMAPEYAM EGRFSEKSDV YSFGVLMLEI VKGVKNTHYY
NQELSLSLLG YAWKMWREDN GLAFADKSIA IADFKEEIIR CIQIALLCVQ EFPKDRPSIQ
TVVSMLSREI VELPPPEQPV FAEKWTGSTQ HSTQVGHIVQ LFILQSIFLY SSFFCLETDT
ISPGLSIRDP DTIVSNRHLF RLGFFTPEAG NTTHRYLAVF YNFSETTVVW VANREKPLVN
DSSGVVKIAD DGNLVLLNSK NQTVWSTNAA AAATTNTTTA QITDSGNLVL RDNATGATIW
ESFSHPSNVY LPTMKISKNI NTGEKVVLSS WRNDRSDPRL GSFTSGIKVL NIPQIFIWKN
GRPHWRSGPW NGRIFMGIKE MYSLYLNTAS IKNDSDGTFY FTVPDRWRLL SMVVLNSSGT
LVQTFYNDQK MSWDVAAMNP STVCDLYGTC GAFGICHTQY SPVCSCLKGF EPTNMAEWGR
GNWTSGCRRI NLLQCTHRNN DTGGGKSGDG FLRLKFVNVP DFAQQYYSAT RKEECRARCL
MNCSCIAYAH DPNIGCMFWS NTTSLIDIQK FNRIGVDLYL RLSASDFEDK KLFIIISVVV
VVVVVVFIIF IAWYWMVKAK GKKINVKKKN DEAGLITYSS DSTEMALKDE SRIVNMKDLL
LFTFEMLANA TDQFHDKNLL GKGGFGPVYK GNLADGNHEI AVKRLSAASG QGVKEFMNEV
IVICKLQHRN LVRLLGCCVD KAEKMLIYEY LPNKSLDIYL FGSSRSILDW KKRFNIIEGI
GRGLLYLHRD SRLRIIHRDL KPSNVLLDED WNPKISDFGM ARIFGGDQDH GNTARVVGTY
GYMAPEYAME GRFSEKSDVY SFGVLMLEIV KGEKNTHYYN QELSLSLLGC AWKLWSEDNG
LAFADKSIAI PDFKEDIIRC IQIALLCVQE FPKDRPSIQT VLSMLSREIV DLPPPEQPVF
AEKWTGSTQP STQVGFSINE LTVSALDGR
//
