ID   A0A022QWU2_ERYGU        Unreviewed;       528 AA.
AC   A0A022QWU2;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=C2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MIMGU_mgv1a004411mg {ECO:0000313|EMBL:EYU32356.1};
OS   Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX   NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU32356.1, ECO:0000313|Proteomes:UP000030748};
RN   [1] {ECO:0000313|EMBL:EYU32356.1, ECO:0000313|Proteomes:UP000030748}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX   PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA   Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA   Schmutz J., Willis J.H., Rokhsar D.S.;
RT   "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT   population shotgun sequencing.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- SIMILARITY: Belongs to the synaptotagmin family.
CC       {ECO:0000256|ARBA:ARBA00006996}.
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DR   EMBL; KI630858; EYU32356.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A022QWU2; -.
DR   STRING; 4155.A0A022QWU2; -.
DR   eggNOG; KOG1012; Eukaryota.
DR   PhylomeDB; A0A022QWU2; -.
DR   Proteomes; UP000030748; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   CDD; cd00030; C2; 2.
DR   CDD; cd21677; SMP_SYT; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 2.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR031468; SMP_LBD.
DR   InterPro; IPR045050; Synaptotagmin_plant.
DR   InterPro; IPR039010; Synaptotagmin_SMP.
DR   PANTHER; PTHR10774; EXTENDED SYNAPTOTAGMIN-RELATED; 1.
DR   PANTHER; PTHR10774:SF178; SYNAPTOTAGMIN-4; 1.
DR   Pfam; PF00168; C2; 2.
DR   Pfam; PF17047; SMP_LBD; 1.
DR   PRINTS; PR00360; C2DOMAIN.
DR   SMART; SM00239; C2; 2.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR   PROSITE; PS50004; C2; 2.
DR   PROSITE; PS51847; SMP; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW   Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00023055}.
FT   TRANSMEM        6..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          60..246
FT                   /note="SMP-LTD"
FT                   /evidence="ECO:0000259|PROSITE:PS51847"
FT   DOMAIN          212..331
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          385..504
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
SQ   SEQUENCE   528 AA;  60489 MW;  C898DCD343BC8A4B CRC64;
     MGFFVGYVLG FGLGMGLIVG FARFQNIRSK HRTDLAQLIA AFARMTVQDL RKLFPDDQSY
     PAWLTWLNHH LDKIWPYVDQ AASEIIRNAV EPILEQYRSS IMSSLKFSKL TLGTVAPQFT
     GVSIIEGESN EIIMELELQW DGNPNIVLDI KTRVGVALPI QVKNIGFTGV FRLIFKPLVD
     EFPCFGAICY SLRQKETIRN AVEDFTWPVR QIIPILAGDY SYLELKPVGT LEVKLIEAKE
     LTNKDIIGKS DPFVELFIRP LRDRIQTSKT INNQTNPIWN EHFEFVVEDF STQHLTIRVY
     DNEGIQTSEF IGCAQLPLAE LEPGKVKDVW LKLVKDLDIQ RDQKNRGKVH LEILYYPLNG
     ESELYNPFDP DFRLTLVEKA FKHANDTDPL KSASPMKRDV IIRGVLSVTV ISAENLPATD
     LFGKSDPFVE LTMKKSDQKN KTRVVSDTLN PEWNQTFEFV VEDGLHELLI LEVYDHDTFG
     KEKMGRCIMT LTRAILEQEF RDTFPIDGTE SGRLNLRLKW TPQTIIRD
//