ID A0A022R1B5_ERYGU Unreviewed; 352 AA.
AC A0A022R1B5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=O-methyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MIMGU_mgv1a009130mg {ECO:0000313|EMBL:EYU32600.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU32600.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU32600.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Cation-independent O-methyltransferase family. COMT
CC subfamily. {ECO:0000256|ARBA:ARBA00034481}.
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DR EMBL; KI630827; EYU32600.1; -; Genomic_DNA.
DR RefSeq; XP_012842897.1; XM_012987443.1.
DR AlphaFoldDB; A0A022R1B5; -.
DR STRING; 4155.A0A022R1B5; -.
DR GeneID; 105963076; -.
DR KEGG; egt:105963076; -.
DR eggNOG; KOG3178; Eukaryota.
DR OMA; MMMTANG; -.
DR OrthoDB; 540616at2759; -.
DR PhylomeDB; A0A022R1B5; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IBA:GO_Central.
DR GO; GO:0019438; P:aromatic compound biosynthetic process; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IBA:GO_Central.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR012967; Plant_MeTrfase_dimerisation.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746:SF327; ACETYLSEROTONIN O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR Pfam; PF08100; Dimerisation; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 25..73
FT /note="Plant methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08100"
FT DOMAIN 160..334
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 257
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 352 AA; 38669 MW; F0BDACA8E72B96DB CRC64;
MGLDEEARAR AEVWNYAFGY INCRVVKCAV ELEIPDIVRK HAGAGAGGPV SLSELSSAVG
VPTEPLHRIM RFLIHHRIFK TSPPPPHAES SSSDEVHYAA TPLSGLLTRD NLAPFMLLQG
TPPGPNRGIT PEALRTGRRP DLKSVNGEDT WSVPDFGYHM KVFTDSMAAH ARVATQAVID
NFPEGFEGIE TLLDVGGRHG MALSMLVKAF PWLRGTVLDL PKIVDHAPPL EGIHFVGGSM
FENIPNSNAV MLMWILHDWS DEACIDILKK CKDAIPKDTG KVMIVEAVID EDGEGDEYAG
ARLSLDMVMM SVMVKGKERT YKEWAYLLEE AGFSRHNVVN IKTVVSVIEA YP
//
