ID A0A022R3Q0_ERYGU Unreviewed; 951 AA.
AC A0A022R3Q0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Lysosomal beta A mannosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MIMGU_mgv1a000882mg {ECO:0000313|EMBL:EYU34856.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU34856.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU34856.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; KI630668; EYU34856.1; -; Genomic_DNA.
DR RefSeq; XP_012840452.1; XM_012984998.1.
DR AlphaFoldDB; A0A022R3Q0; -.
DR STRING; 4155.A0A022R3Q0; -.
DR GeneID; 105960789; -.
DR KEGG; egt:105960789; -.
DR eggNOG; KOG2230; Eukaryota.
DR OMA; AWPNLHW; -.
DR OrthoDB; 2504097at2759; -.
DR PhylomeDB; A0A022R3Q0; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR043534; EBDG/EBM.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041351; Ig_GlcNase.
DR PANTHER; PTHR43536; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43536:SF1; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF18368; Ig_GlcNase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748}.
FT DOMAIN 210..329
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 343..477
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 866..941
FT /note="Exo-beta-D-glucosaminidase Ig-fold"
FT /evidence="ECO:0000259|Pfam:PF18368"
SQ SEQUENCE 951 AA; 107672 MW; E4CE37A1102E4D4A CRC64;
MAEAIGKRVL DKGWLAARST EVDLTGVELT TTTPPSSDHS PWIEALIPGT VLATLVKNKL
VPDPFYGLEN ESIIDIADSG REHYTFWFFT TFECNLSTNS YVELNFRAIN YSAEVYLNGH
KEVLPKGMFR RHSIDVTEFL NSSGENMLAV LVYPPDHPGT IPPEGGQGGD HEIGKDVAAQ
YVEGWDWMAP IRDRNTGIWD EVSLSFTGPV KIVDPHLVSS FFDDYKRAYL HTTVELVNKG
DLVADCTLNI QVGTEPEGDL ILVEHLQTQK LSIPAGSHVQ YTLPELFFYK PNLWWPNGMG
KQSLYNVEIT VDVEDHGESD SWSEHFGFRK IESDIDTTTG GRLFKVNGEP IFIRGGNWIL
SDGLLRLSKK RYKTDIKFHA DMNFNMIRCW GGGLAERPEF YHYCDIYGLL VWQEFWITGD
VDGRGVPVSN PDGPLDHDLF LLCARDTVKL LRNHPSLALW VGGNEQVPPD DINTALKNDL
QLHPYFETNF ESNKNFKKEI SPILKDPSEY LDGTRIYVQG SMWDGFANGQ GDFTDGPYEI
QNPENFFKDD FYMYGFNPEV GSVGMPVAAT IRATMPPEGW QIPLFNKLAS GYIEEVANPI
WVYHKYIPYS KPGLVHDQIL LYGTPKALDD FCLKAQLVNY IQYRALLEGW TSRMWTKYTG
VLIWKTQNPW TGLRGQFYDH LHDQTAGFYG CRCAAEPIHV QLNLSTYFIE VVNTTSKELS
DVAIEASVWD LEGACPYYEV FDTLTIPSKT TLSTSEIKYP NSDNAKPVYF LLLKLYKKSD
DDKKIISRNF YWLHLPGGDY KLLEQYKSNK IPLKIMSLTF IKGSSYEVKM HIQNTSSNNG
DFVDREKGQS WFRKILKNFP KKGSEVKVTE IGGAQSGVAF FLHFSVHTSE KDEKKGEDTR
ILPVHYSDNY FSLVPGEVMA VTLNFEAPEG VTPCVLINGW NYEGGVVVSL A
//
