ID A0A022RAC6_ERYGU Unreviewed; 944 AA.
AC A0A022RAC6;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=MIMGU_mgv1a000916mg {ECO:0000313|EMBL:EYU35870.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU35870.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU35870.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCA family.
CC CPR flippase (TC 3.A.1.211) subfamily. {ECO:0000256|ARBA:ARBA00008526}.
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DR EMBL; KI630593; EYU35870.1; -; Genomic_DNA.
DR RefSeq; XP_012839392.1; XM_012983938.1.
DR AlphaFoldDB; A0A022RAC6; -.
DR STRING; 4155.A0A022RAC6; -.
DR GeneID; 105959786; -.
DR KEGG; egt:105959786; -.
DR eggNOG; KOG0059; Eukaryota.
DR OMA; MSVEWAL; -.
DR OrthoDB; 451002at2759; -.
DR PhylomeDB; A0A022RAC6; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005319; F:lipid transporter activity; IBA:GO_Central.
DR GO; GO:0006869; P:lipid transport; IBA:GO_Central.
DR CDD; cd03263; ABC_subfamily_A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF154; ABC TRANSPORTER A FAMILY MEMBER 11-RELATED; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 622..859
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 944 AA; 105350 MW; F703D6642FB82FCD CRC64;
MADSTNEQSS FWTQANALLR KNLIFQKRNM KTNIRLVLFP LVLCLLLVLI QVLVNTQLDK
PSNRCGCICV DTGKGPCEKK CGIEYSTLEQ ASSCPIPHPP EWLPLLQVPS PQFRAVRTDF
TSYGDLPGDS CRKTGSCPVT TLVTGNNQTF GQTVAGNMFS RPLNIDSSDL LYSLADNALG
SETDTRFTNF LDTAFLSNVP IDILQPQCSS NSQISVTIQL GATALEKDIR CAQGLQLWRN
SSSEINSELY KGYLKGNPES KINEILAAYD FVNSKDNLFN VTIWYNSTYR SDTGNQPLNL
IRVARSINLA SNAYLQSLLG PTAEMLFEFV KEMPKPETKL RLDFSSLLGP LFFTWVIVQL
FPVVLISLVY EKEHKLRIMM KMHGLGDGPY WMISYAYFLA ISSIYMLCFV LFGSAVGLNF
FRLNDYSIQF VFYFLYINLQ ICLAFLVADW FSSVKTATVV GYMMVFGTGL LGGFLFQFFL
EDSSFSKAGV IAMELFPGFS LYRGLYEFSQ YAFNGNYMGT GGMEWKDLND SNNGMREVLI
ILAVEWLVVF GVAYYADQVV SSGTNPLSFL RKKQKNLQSS FRKPSLRRQG SKVFVQMEKL
DVDQEREKVE QLLLESSTSH SIICNNLKKI YPSRDGNPEK FAVRELSLAL PQGECFGMLG
PNGAGKTSFI NMMIGLIKPS SGTAYVQGLD IRTDMDRIYT SMGVCPQHDL LWETLTGREH
LLFYGRLKNL KGAALTQAVE ESLKSVNLFH GGVADRKAGK YSGGMKRRLS VAISLIGDPK
VVYMDEPSTG LDPASRNMLW NVVKRAKQNR AIILTTHSME EAEHLCDRLG IFVDGSLQCV
GNPKELKGRY GGSYVFTMTT SPTHEEEVEN LVNQLSPNAT KVYQISGTQK FELPKNDIRI
ADVFEAVGNA KSRFTVQAWG LADTTLEDVF IKVAKGSQAD STLS
//
