ID A0A022RBT9_ERYGU Unreviewed; 1188 AA.
AC A0A022RBT9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Eukaryotic translation initiation factor 5B {ECO:0000256|ARBA:ARBA00013824};
DE AltName: Full=Translation initiation factor IF-2 {ECO:0000256|ARBA:ARBA00032478};
GN ORFNames=MIMGU_mgv1a000394mg {ECO:0000313|EMBL:EYU37802.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU37802.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU37802.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
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DR EMBL; KI630513; EYU37802.1; -; Genomic_DNA.
DR RefSeq; XP_012837054.1; XM_012981600.1.
DR AlphaFoldDB; A0A022RBT9; -.
DR STRING; 4155.A0A022RBT9; -.
DR GeneID; 105957653; -.
DR KEGG; egt:105957653; -.
DR eggNOG; KOG1144; Eukaryota.
DR OMA; APNQNED; -.
DR OrthoDB; 561106at2759; -.
DR PhylomeDB; A0A022RBT9; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR CDD; cd03703; aeIF5B_II; 1.
DR CDD; cd16266; IF2_aeIF5B_IV; 1.
DR CDD; cd01887; IF2_eIF5B; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR029459; EFTU-type.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 5B; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF14578; GTP_EFTU_D4; 1.
DR Pfam; PF11987; IF-2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748}.
FT DOMAIN 597..813
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..339
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..523
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..556
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..594
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1188 AA; 132853 MW; B7E26526AFE375FC CRC64;
MGRDNVELKN NKSTSMGGKK SKKNGFLIDD NEYSIGTELS EYSVLVPESK VAPLGKQMKT
DLNNEDEQVE DDYDVPVIKF DGRNKSKGKK SACFSASSFE LLGEDEDEND YGRNDNDEEL
GSPVIAFSGK KKHSKSGCGV SSAFDLLGKD KDDSSKEEDE DIGITFTGKK KKSSKGLNKA
SGNSFSAAVL DEENGEDASV SNESSKIWNG DASSDFVEPE KRSDDSKIKK QTGEDPTDTS
KNKKKKKKKN KGGKTGDEED DLDKILAELG VVLPESTCIA APTVVQHRGE LEEAADADKE
NEDEGPVGSV TSKKKKKKKK KDKEKEKKAA HEKQEETKIE TNSNVLGKKV PKHVREILAK
QKEAEEKKKQ EKEERQRKEE EEQRRVEEEQ EEQRLMEEKK RLKREKEKEK LLKKKQEGKI
LTAKQKEEVR KREAMRTQFL ANAGGLQLPS GEPSAKRPLY QKKKAKAQQA QPNGASASDN
VEITDSKEIQ HEFSLARDSD AVDLVEENGV HDEEEDEEWD ANSWDDSDLK LPGKSAFEDE
DVDTKPEPKE IKNSRNATQD VELASITTKP RDFIEEKKNI KQVPKEESPN SDDKNELRSP
ICCIMGHVDT GKTKLLDYIR GTNVQEGEAC GITQQIGVTY FPAENIRERT RELKADAKLN
VPGLLVIDTP GHESFTNLRS RGSGLCEIAI LVVDIMHGLE PQTIESLNLL KMRNTDFIVA
LNKVDRLYGW KTCRNAPIAK AMKQQSKQVQ MLFNDRLIQI ITQFKEQGLN TELYYKNKDR
GDTFNIVPTS AISGEGIPDI LLLLVQWTQK TMIERLTFSK EVECTVLEVK VIEGHGTTID
VVLVNGVLHE GDQIVVCGLQ GPIVTTIRSL LTPHPMKELR VKGTYLHHKE IKAAQGIKII
AQGLEHAIAG TSLYVVGPDD DLEDVKNKTM EDMKSVMSRI DKSGEGVYVQ ASTLGSLEAL
LELLKTPVNI PVRGISIGPV HKKDVMKASV MLEKINEYAT ILAFDVKVTQ EARELADELG
VRIFTADSIY QLLEQFKAYI NNLKEERKRE AAEEAVFPCV LKIVPNCVFN KKDPIVLGVD
VVEGTLKIGT PICVPQKEFI EIGRIASIEN NHKPVDYAKK GQSVAIKIVG SNSEDQQKTF
GRHFDIDDEL VSKISRSSLD ALKQNYKDEV SQDEKNLLFK LKRLFKIP
//
