ID A0A022REE4_ERYGU Unreviewed; 435 AA.
AC A0A022REE4;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Apyrase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MIMGU_mgv1a006675mg {ECO:0000313|EMBL:EYU37260.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU37260.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU37260.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283, ECO:0000256|RuleBase:RU003833}.
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DR EMBL; KI630555; EYU37260.1; -; Genomic_DNA.
DR RefSeq; XP_012837696.1; XM_012982242.1.
DR AlphaFoldDB; A0A022REE4; -.
DR STRING; 4155.A0A022REE4; -.
DR GeneID; 105958239; -.
DR KEGG; egt:105958239; -.
DR eggNOG; KOG1385; Eukaryota.
DR OMA; GEQYEAM; -.
DR OrthoDB; 180318at2759; -.
DR PhylomeDB; A0A022REE4; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IBA:GO_Central.
DR GO; GO:0009134; P:nucleoside diphosphate catabolic process; IBA:GO_Central.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF124; APYRASE; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
DR PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Hydrolase {ECO:0000256|RuleBase:RU003833};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..435
FT /note="Apyrase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001505056"
FT ACT_SITE 156
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 186..190
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 435 AA; 47394 MW; 79DD93E66C0A928A CRC64;
MMSYSSLLLQ LLLLMNYGQD DEVIKIENIN NYAVVFDAGS TGTRVHVYSF DRNMDLLPVG
NDYEFFLSTK PGLSSYENDP EGGAQSLKPL LQKAQDVVPQ QFLANTPVIL GATAGLRQLP
ASATEAILDA VRNLFKNESK LSYKADWVST LQGTDEGAYQ WVTVNYLLGT LGKKYSSTVG
VVDLGGGSVQ MAYAISDKSA ANAPKDEDAY VMDKLVMGTK YNLYSHSYSN YGQKAGRAQS
LNLSGDAGNP CVTNGYQGTY EYLGVVYNVS APLSGTSMRR CRALMRKTLR VDAPCNHTYC
SFDGVWSGGG GLGLKNLYVA SYFYDTAAET GLVEADAPSG KIRPIYYKNA AKKACSATVD
NIKSIFPLLD ERDVPFLCSD LIYEYTMLVD GFGVNQLKEI TVVKQLEYKK DSSLPLLEAA
WPLGCAVELV SSLVN
//
