ID A0A022RZK5_ERYGU Unreviewed; 925 AA.
AC A0A022RZK5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=MIMGU_mgv1a023751mg {ECO:0000313|EMBL:EYU45932.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU45932.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU45932.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; KI630171; EYU45932.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A022RZK5; -.
DR STRING; 4155.A0A022RZK5; -.
DR eggNOG; KOG1052; Eukaryota.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF415; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT TRANSMEM 567..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 811..832
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 439..787
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 735..790
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 925 AA; 101842 MW; 8AE35FA0362DF978 CRC64;
MAVASGAANA SETAATAATE SSPNNSTFRV GVILDLDSLI GRTGVNSLSL ALSDFYSVNS
NYTTRLVLHV RNSNEQVLDA ASAALTLLKE LEVDAIIGPQ ESEQANFLIR LGERANVPFI
SFSVTSPAVV HPSSSYFVQT AITDSAQVGA IASIIKHFQW NQIVLVYEDS HYGNSIIPYL
VKSFQEVNAR VTYRNSIATS ATDDNVLQEL YRMKTMQTRV FVVHMSSSLA SRFFPHAKRA
GMMVDGYAWI LTSRLMDSLY SFESHVVIES MQGVLGVKPL IPRSEKLTSV SQRWKTKFVH
DNPNYALQAE LGLYGVWAYD TLFALAMAAE RVKLRLPTSS QKTRFFDTEI SLTGPKLLEA
ISEVTFKGLA GNFRLLNKQL EPSSFQILNV VGTGDREVGI WTPNEGIINK KLKSVIFPGE
STVVPKGWEV VPAGGNKLRI GVPVQPGFSE FVKVEKDPRN NATLFSGCYI DTFDDVMAKL
PYPVPYEFVA FEKSDGSSAG SYDELAYQVF LQNYDAAVGD ITITYNRSKY VDFTIPFSEG
GVDIIVPIAY DDLNSKWIFL KPLAKDLWLT AIALFILTGV ALWILEHRFN SAYRGPPSNH
AGMIFYFPFM SLVFAQRERI VSNLARLVVV VWMFVVLILS STYTASLSAR LTVQRLQPAV
TDVLQLTRKG DFVGCHKGSF IFDLLQDLGF DKSKIKLYEL PVEVHEALSE GSEKGGISAF
FSVRAYTKLF LSNYCNKYTT VGPTYPTEGF AFVFPKASVL VADVSRAIIE QMQNGRIKGI
ERQWIKNPMC SGGSDGTVAS NSVPLQSFRT LFGVTGGITA TCVAVFLCRY LYQNRYFVRT
VTSSSNTTFW SKVREVCKHF DGRENAATIG TNLVGNSSPR SSSTVVPVSS VHVEIIDGVN
TVESISESAS ESTSESVSVS ESTIV
//
