ID A0A022S2B5_ERYGU Unreviewed; 549 AA.
AC A0A022S2B5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Methyltransferase type 12 domain-containing protein {ECO:0000259|Pfam:PF08242};
GN ORFNames=MIMGU_mgv1a004018mg {ECO:0000313|EMBL:EYU46474.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU46474.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU46474.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. METL family.
CC {ECO:0000256|ARBA:ARBA00009725}.
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DR EMBL; KI630171; EYU46474.1; -; Genomic_DNA.
DR RefSeq; XP_012831403.1; XM_012975949.1.
DR AlphaFoldDB; A0A022S2B5; -.
DR STRING; 4155.A0A022S2B5; -.
DR GeneID; 105952403; -.
DR KEGG; egt:105952403; -.
DR eggNOG; KOG2361; Eukaryota.
DR eggNOG; KOG2497; Eukaryota.
DR OMA; MDRRWIQ; -.
DR OrthoDB; 5471626at2759; -.
DR PhylomeDB; A0A022S2B5; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:UniProt.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0001510; P:RNA methylation; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR026113; METTL2/6/8-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22809; METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR22809:SF5; TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 74..175
FT /note="Methyltransferase type 12"
FT /evidence="ECO:0000259|Pfam:PF08242"
SQ SEQUENCE 549 AA; 61631 MW; DAEC4D16DA3E3C60 CRC64;
MASPSDVVQQ GKIQIYSPSN DEVSAFWRDK YEKDAKKYWD IFYKRHQDKF FKDRHYLEKE
WGHHFSEEGT KAILEVGCGA GNTIFPLLAA YPDIFVHACD FSPRAVNLVK MHKDFTEARV
NAFVSDLTID DLSVQLAPSS VDIVTMMFVL SAVSPEKMPT VVQNIRKVLK PNGRILFRDY
AIGDLAQERF TGKEQKISEN FYVRGDGTRA FYFADEFLRN LFEENGFSMV EHVLCCKQVE
NRSRELVMNR RWVQAVFQLA DTKCISGAKT KDESVHLQEG CERKDDVNGF EIDISDGVAV
EMFGISSSSE EIIEISIRDY FFKIKVLSKE YQHTCPSTGL MLWESARLMA SVLAANQEIT
SGKRVLELGC GCAGVCSMIA VGSANLVVAT DGDTKALDLL TQNVASNVKP QFLDSLHVKR
LEWGNEEDTE AIKKLSDIGF DIIIGTDVTY VKEAIIPLFA TARALISTGV SGESIKDRGL
ILCHVLRRVD EACILSAAAR YGFKLVERWP ESDETSNSSY GGGIIKNWLS NCQYEVPTTA
LNIMYFHIA
//
