ID   A0A023B441_GRENI        Unreviewed;       895 AA.
AC   A0A023B441;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Putative sortilin {ECO:0000313|EMBL:EZG56353.1};
GN   ORFNames=GNI_104190 {ECO:0000313|EMBL:EZG56353.1};
OS   Gregarina niphandrodes (Septate eugregarine).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Gregarinasina;
OC   Eugregarinorida; Gregarinidae; Gregarina.
OX   NCBI_TaxID=110365 {ECO:0000313|EMBL:EZG56353.1, ECO:0000313|Proteomes:UP000019763};
RN   [1] {ECO:0000313|EMBL:EZG56353.1, ECO:0000313|Proteomes:UP000019763}
RP   NUCLEOTIDE SEQUENCE.
RA   Omoto C.K., Sibley D., Venepally P., Hadjithomas M., Karamycheva S.,
RA   Brunk B., Roos D., Caler E., Lorenzi H.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EZG56353.1}.
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DR   EMBL; AFNH02000778; EZG56353.1; -; Genomic_DNA.
DR   RefSeq; XP_011131282.1; XM_011132980.1.
DR   AlphaFoldDB; A0A023B441; -.
DR   EnsemblProtists; EZG56353; EZG56353; GNI_104190.
DR   GeneID; 22913702; -.
DR   VEuPathDB; CryptoDB:GNI_104190; -.
DR   eggNOG; KOG3511; Eukaryota.
DR   OMA; GGHWSYL; -.
DR   OrthoDB; 5840at2759; -.
DR   Proteomes; UP000019763; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR   Gene3D; 2.10.70.80; -; 1.
DR   Gene3D; 3.30.60.270; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR031777; Sortilin_C.
DR   InterPro; IPR031778; Sortilin_N.
DR   InterPro; IPR006581; VPS10.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR12106; SORTILIN RELATED; 1.
DR   PANTHER; PTHR12106:SF27; VPS10 HOMOLOG 1-RELATED; 1.
DR   Pfam; PF15902; Sortilin-Vps10; 1.
DR   Pfam; PF15901; Sortilin_C; 1.
DR   SMART; SM00602; VPS10; 1.
DR   SUPFAM; SSF110296; Oligoxyloglucan reducing end-specific cellobiohydrolase; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019763};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..895
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001511470"
FT   DOMAIN          46..788
FT                   /note="VPS10"
FT                   /evidence="ECO:0000259|SMART:SM00602"
FT   REGION          383..413
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        384..405
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   895 AA;  98806 MW;  D883DD9AEE7ABFD2 CRC64;
     MLRRLLWLIC LLLPGLAALT DKKVDVTPTR FDSGLSDIQW LRQDHSVVMV LTTRGHVWRS
     PNSGRTFQDI TYTVDKTLDK SEAESVTTPN NTVARGPPVR PERFFEFIKV HPTNKNYAVL
     LTKGDQTYLT MNAGITWYPL GRRTFVHNWV WHPLRPTHAL MSEWTAGCRG RRPGPTIGDC
     NHQLYITTNG GRTVSKVADF VIQYNWGDKS LKEQADAIFM TQHTRVRKHQ PRWGGWHANT
     EFVKLTNWGT KRHVLVPGGN KFLVAKDFVF VATVDDYLRQ TVSLMVSSDG GRSFNKAQIP
     SSKMMEKSYT ILDTSGGNVL IHVNHGSTSP GILEGNVYVS DSTGTKFSLS LPNNIRAATG
     ECEFDKVVGV EGVYIANTRS DSVLEGGDGE EDLRRAGEED EEGSMGMMKA ASSRRQTSPV
     VRTVISFDKG GSWQYLKPPT KDTLGNRISC EDSQKCWLHL HGITHFDRFA PFYSSENALG
     LVMGTGNVGA HLSRDAADIN TYISRDAGRT WAEAHKGSYI YEFGDHGGLV VMAHDNKKTG
     QVVFSWNEGQ SWYDFTLGMN DVAVDNVIIE PTSTGLEFLV YGTIGEKGVL FHTDFGTLNQ
     RQCIGMTRPD NPSKLDLSSA VAAGTVAGTV AAPVGAEGVV NAENSGPGLD QLSGGGSPAG
     GSDYEYWYTS QEEQNSRCML GRRVKYVRKK PYRECFNGKD FVRLKDKHTC ECSRENYMCE
     TGFFRPVNHE TDAECEPSPY EDREYMAIEG CTSSGVYYTH AWRKVPGDEC KGGWAPEKVP
     MPCPPGSPMA APARATLWTV VLSAVALGAL SWASKHPLLR PYVQRAGLDQ FVEVGYSVVG
     KAGESMQRGG EELFNFWTGK PEDENVTTTA ALTLSNPPAS HAAGIELNTT RLDII
//