ID A0A023B9W3_GRENI Unreviewed; 507 AA.
AC A0A023B9W3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN ORFNames=GNI_045660 {ECO:0000313|EMBL:EZG76056.1};
OS Gregarina niphandrodes (Septate eugregarine).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Gregarinasina;
OC Eugregarinorida; Gregarinidae; Gregarina.
OX NCBI_TaxID=110365 {ECO:0000313|EMBL:EZG76056.1, ECO:0000313|Proteomes:UP000019763};
RN [1] {ECO:0000313|EMBL:EZG76056.1, ECO:0000313|Proteomes:UP000019763}
RP NUCLEOTIDE SEQUENCE.
RA Omoto C.K., Sibley D., Venepally P., Hadjithomas M., Karamycheva S.,
RA Brunk B., Roos D., Caler E., Lorenzi H.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EZG76056.1}.
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DR EMBL; AFNH02000350; EZG76056.1; -; Genomic_DNA.
DR RefSeq; XP_011129590.1; XM_011131288.1.
DR AlphaFoldDB; A0A023B9W3; -.
DR EnsemblProtists; EZG76056; EZG76056; GNI_045660.
DR GeneID; 22911712; -.
DR VEuPathDB; CryptoDB:GNI_045660; -.
DR eggNOG; KOG0166; Eukaryota.
DR OMA; GGFHETQ; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000019763; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 6.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000019763};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT DOMAIN 1..52
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 105..148
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 148..191
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 323..365
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 507 AA; 56052 MW; 30288608D84584EB CRC64;
MESRIDTRRK DFKKSFEDPL RLRESEQVQI RKAAREARLN KKRMEASPAP GVVSQEASSV
TSIPVEVCEA LASDDRDRQC EAAKEIRHML SLHSNPPIQP VIDAGLVPRF MELLRMDSRP
DVQFEAAWAL TNIASGDSAQ TSAVVQAGAI PEFVRLLDSE HLQVKEQSVW ALGNIAGDCR
QLRDAVIQAG GFFPILRELR QTDQTSRMYL LRYATWTLSN FCRGPMAEPY EIVREALPVL
RSLLYSNDPE IITDACWSIS YMSDTNNGPN SNVINEIIRN GVCGRLVELL SHRSHLVQTP
ALRAVGNIVT GDDTQTQTMI SYGCIPKLKE LLTASMKPIR KEACWALSNV TAGNKTQIQE
VIEAGVLPVI AQALANDDYE VRREAAWCVA NAASGGAEQQ VRAVVDAECI GPLVSVLDAI
DPKVAGIALE AIENILKVGK KRQIDENLPC NPYAEKLEEA EAFPKLEKLQ FIGKTTIQTR
AIHIMTEYLE AYVDEPARPT GFGGMAN
//
