ID A0A023BPQ3_9FLAO Unreviewed; 4622 AA.
AC A0A023BPQ3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ATO12_04935 {ECO:0000313|EMBL:EZH71966.1};
OS Aquimarina atlantica.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Aquimarina.
OX NCBI_TaxID=1317122 {ECO:0000313|EMBL:EZH71966.1, ECO:0000313|Proteomes:UP000023541};
RN [1] {ECO:0000313|EMBL:EZH71966.1, ECO:0000313|Proteomes:UP000023541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=22II-S11-z7 {ECO:0000313|EMBL:EZH71966.1,
RC ECO:0000313|Proteomes:UP000023541};
RA Lai Q.;
RT "Aquimarina sp. 22II-S11-z7 Genome Sequencing.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EZH71966.1}.
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DR EMBL; AQRA01000010; EZH71966.1; -; Genomic_DNA.
DR RefSeq; WP_051575998.1; NZ_AQRA01000010.1.
DR STRING; 1317122.ATO12_04935; -.
DR eggNOG; COG1028; Bacteria.
DR eggNOG; COG3321; Bacteria.
DR eggNOG; COG4221; Bacteria.
DR OrthoDB; 1230081at2; -.
DR Proteomes; UP000023541; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd08953; KR_2_SDR_x; 3.
DR CDD; cd00833; PKS; 3.
DR Gene3D; 1.10.1240.100; -; 3.
DR Gene3D; 3.40.47.10; -; 3.
DR Gene3D; 1.10.1200.10; ACP-like; 3.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 3.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 3.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR049490; C883_1060-like_KR_N.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF21394; Beta-ketacyl_N; 2.
DR Pfam; PF16197; KAsynt_C_assoc; 3.
DR Pfam; PF00109; ketoacyl-synt; 3.
DR Pfam; PF02801; Ketoacyl-synt_C; 3.
DR Pfam; PF08659; KR; 3.
DR Pfam; PF21089; PKS_DH_N; 3.
DR Pfam; PF00550; PP-binding; 3.
DR Pfam; PF14765; PS-DH; 3.
DR SMART; SM00826; PKS_DH; 2.
DR SMART; SM00822; PKS_KR; 3.
DR SMART; SM00825; PKS_KS; 3.
DR SMART; SM00823; PKS_PP; 3.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 3.
DR SUPFAM; SSF53901; Thiolase-like; 3.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 3.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000023541};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 798..874
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 933..1368
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 2318..2394
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2442..2867
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 3586..3659
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3713..4145
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 4622 AA; 519845 MW; B9A82F5EC950B985 CRC64;
MIDFIEYVVL ELKSKRLSKA NALDLIKQFS HRTVTHANRD IIHPLLHKNT SDLSQQSFST
TFNGKELFLK DHMVKDQKVL PGVAYLEMAR MALRQALPFQ EESIVELRNV IWAQPIIVEN
PKEVTIALFA DEAEISNGQI NYEVYSTEPG TEESVKETIH CQGQAVYINT SKPTRLDIDK
LKIEMQQGEL KSTPIYAAYS KLGLKYGPTY RGIKTIFRDN GQLLAQLELS EIAKSNFEEY
VLHPGVMDSA LQSAIGLLGD LDQIPDKPSL PFALESLKVF SGCTKEMFAW VRYSKGNKPT
NKVTKLDIDL CNEKGEVAIQ MKGFSSRMLN EDSVTKEATV TKKGVLYGAP VWQVTNDMKP
FSQNGTDIVK HRYVFLCEVP QVDTKQLESL LTSSKVIHLQ NTQQKNIAER FSEYAQICFE
QLRMILGDKL QEKVLIQIVT TSKSEQSIFT GLSALIKTAT LENPKLAGQV IITHPEITTE
KLIIQLEENQ NKTQDTIIKY EQETRQILRW KEIPLVHNKP KIVFKDNGVY LITGGLGNLG
KILVREILKQ TQNAKIIVTG RSELTEEKQI LIDEIDGKAG RLFYKQLDIV DLDKVKRIIT
SIKKEHKGIH GIIHSAGMIS DSFILKKTSE EFSKVLAPKV LGTYNLDEAS KNIDLDFLVL
FSSISSITGN GGQADYATAN NFMNQFAMYR NQLVEAKQRS GKTMTINWPL WEKGGMKIDQ
LKQEMLEQST GMLPMSSETG VHAFYRSLEL TQDQLLVVEG NVEKLHQTLF NDNASETSLS
GSITSVKEEL VVEMDEENLE EQTQNYIKKQ LSELFKLPPH KIDSFAPLEK YGIDSILAMN
LTNELEKTFG SLPKTLFFEY QTIHELTNYF INSHLSKLTA LFISGFEKDN LEKNKDMSID
SPIEAQSKQG KSRSIKRLRK IGVSVDKKNS VDTDPIAVIG LSGRYPKASN IEAYWNNLRD
GKDCITEVPK NRWDWQEYYS PDRSKSGYHY SKWGGFIDGV DEFDPLFFNI SPLEAEILDP
QERLFLQHTW MAIEDAGYTK ASLQIPHEFG QAGQVGVYAG VMYSEYQLYG IEASKRGHRM
GVPGSYASIA NRVSYVLNLH GPSMTVDSMC SSSLTAIHLA CQDLKQGRTS LGIAGGVNVS
IHPNKYTVIS AGQYISSEGH CQSFGEGGEG YIPGEGVGVV VLKRLSEAEK DGDHIYGIIN
GSTLNHGGKT NGYSVPSPKA QSNLISNVLK ETNTDPRHIS YIEAHGTGTK LGDPIEISAL
NKAFKQSTSD IGFCLLGSAK SNIGHCESAA GIAGLTKVLL QLKHQQIVPS LHSKNLNPNI
DFEKTPFIVN QTLRTWEQPI INGIPQPRIA GVSSFGAGGA NAHIIVQEYI VPTKVSQPKI
SIDLDSKAII PLSARTQDQL KQKAIDLYDF LQKTKIEKQE QVIAPIDLTE MAYTLQVGRE
TMDMRLGFMV NSVEELIQKL KAYINGEKNI EDTYQGHTDT DKDTLLVFNA DVDFEQTVDK
WIARRKWSKL LDLWVKGLNL DWNKFYEGNT PKRISLPVYP FAKDKYWIDI KMNDQSTVDR
KITSVLHPLL HSNTSDLSKQ SYSSIFSGEE FFLADHQVKI KEGKISKVLP AVAYLEMARV
AVEKAVPVKA KSSILELHNT AWAQPLVVEK DKQVEIALYI KKENQIDYEI YSTDNEQDII
HCQGVATYST HLSLEKLSIE QLKEQMNRGS IEAASLYFTF KSMGLVYGPA YQGITKIYQG
EKQLLVQLNL PSVVKTNQND YLLHPSLMDS SLQAAFGLID DLTTIPSQPS VPFALETIRI
LSAVTEHMFA WIRYSEGSLA TDAVTKLDID ICDQEGNICV QMKGVSSRQL SEDTIDFKNE
DIGILMAKPL WKSFKIPQIP ETPKAEFAEK HVILCEMSDI ETSQLQTLIH YNHCIQLEAS
QKNIAERYTD YALTCFEHVQ TILKNKPKAK ILIQIVITDN KEQALFSGLS GLLKTAAQEN
PMLTGQMILT KSAIQTKELV RQLQKATTIS EESIVKYEND TSYILQWDEV KANQENSKPV
FKNQGVYLIT GGLGALGVLF AKEILQQTNE TKIVVTGRSE LTEEKQIILN ELTSDTNQVE
YQQLDLNSLE QVEKLIATIE RENGKLNGII HSAGMISDNF ILKKTSAEFN KVLAPKVTGT
YNLDQASKDI HLDFLVLFSS LSGAMGNLGQ SDYATANAFM DQFTRYRNQL VDQKLRQGHT
LSINWPLWES GNLSIAQKNI EILWQETGIS PIQTSSGIQA LYSSMTLQGN QVLVMEGNVN
KIRSILLSKQ TRKVEQMSKS TSSQNVETAK TATIDSNTLL DKTINYLRKL FAEVLKIKTK
ELDPKAPLEN YGIDSILAMR LTNILEKTFG SLSKTLFFEY QTIKSLAEFF ARTYPQIIQE
RTGIQQTVSS SIELPQDSIK KQSLVSQTYS SNRFFNTTTN TQKEVAIVGL GGKYPLAENV
EEFWENLKKG RDCITEIPEG RWDTDRFFDP KRNQVGKSYS KWGGFISDVD KFDPLFFNIS
PKEAELIDPQ ERLFIQTAWQ TIEDAGYSKE SISTLGRVGV YVGVMYGQYQ LYGAEAMLAG
NAVVPGSSYA SIANRVSYFL DLHGPSIALD TMCSSSLTAI HQACEEIRKG EIEAAIAGGV
NVSIHPHKYL MLSQGNFAAS DGRCRSFGEG GDGYVAGEGV GAVLLKSLDQ AIKDGDHIYG
IVKSSVINHG GKTNGYSVPN PNAQGDLIRE SLKKAKISPS TLGYIETHGT GTALGDPIEI
TGLNKAFGES TPQKQVCPIG SVKSNIGHLE SAAGIAAVTK VLLQLKHKEL VPSLHATTLN
PNINFKESPF YVQQELAPWK SNEEHPRRAS ISSFGAGGSN AHLIIEEYKN NTSKETESYY
NRPQSFVLSS RDKNTLLRYG KKMTDFLRRN KNIELEDLVY TSQVGRTPMN ERLVIVTTHI
NELIEKLDQW LSIYETEDDT LLKRSADELE GVFYGNIKNA SSDTITLLEG EEGKAYLKVI
IEAHNQEKLA KLWISGADID WSLLYQNVQP KRISLPTYPF AKERYWITKP VLPIATNSLE
IQENNAENTS EEEKKKLHYC TKWIEQNLDV SEEKSSENGF ILILDTSDEL FLTLKKQSHQ
YLQGNSYILL KPGSAFEEIE PSVFTIDFQK EENFTQLVEH LNIKEQLPYR IIHNGLEIGS
LDKKENITHQ LNYSIYALFN LCKTLIEQKH QVSLQILSIF LGDTDLTVPC NAALGSFFKT
LTLENPYYKG KIVEVKDSKQ TPIVEKIRMI ENEFSDENWR KNEIRYDLRK NEQTYVRYVK
NLIPLTDVER NINRLPIKQN GVYIVSGGLG GLGLIFSEYL VKNYQSNLVL FGRSPLKAAQ
KKKLDRLKAY GSKILYLQAD ASKLEDVETI VKTAKTNFLQ INGVIHSAGI NQDSFILKKP
KGQIDRVLAP KIYGTTNLDL ATRDENLDVF IMFSSIAGVL GNVGQSDYAY GNHYLNSFAE
NRETLVRERK RHGKTLAINW PYWEEGGMHI SNEEVTLIQK ETGLCPIPVT EGIQFLEEFL
LSDISQCIPL YGFPSKIKTY IDQTTKKTEK NKLTQANIID TDTLFENTVE YLKTLIGKEI
KLDPNRIDPE EHFESFGIDS ISINQINLSL ERDLRDLSKT LFYEYSTIEE LAKYLIQEEQ
ETLIQFLHSE DLINVSSNHV NPLYETKTQR EPIREDKREM KDVMDTPIAY EDSEPIAIIG
VHGSYPQSED LDSYWESLKQ GKDLTDLVPK SRWDFEEFYH EDPEKASEGK IYGKWGGFIS
DVDKFDPHFF NITPEEARIM DPQERLFLQS VWATIEDAGY TKDSLKKRYP KAKSANVGVF
VGVTTNTYNL LASEEWSKGD TIPSAHPWSI ANRISYLFDF NGPSMPVDTA CSSSSVAIHL
ACESLKKQEC KVAVAGGVNL YLHPSKYHSL CKNRMVSLGG KCHSYGKGDD GFVPGEGVGS
VLLKPLSKAI EDGDHIYGVL AGSAFDHSGK SNGYSAPNPN SQANLIEHTL QKAQIHPETI
SYVEGHGTGT QLGDSLEIVA LTNAFQKQTI QKQITAIGSV KSNIGHPESA AGIAGVAKVL
LQMKHQQLVP TINSDQVNPN INFKESPFYL QHKLTPWEPP SGYPRRALIN SFGAGGVNAC
LILEEYRKIK EVYPKQGPHL VIFSAKNEER LQEYVNRVLN YIEKEKQVNL ADLSFTLQVG
REAMSDRLAI VASNREELII RLKDWKQQNE SNYIFWGKLN SNQRRKKTLN REEEFRSLFD
RGDLDKLAQL WVGGVEIDWE KLYTNNKPNR ISLPTYPFAK ERYWVSDRVI EEKKTATEPI
DAQLHPLISY NSSTLREVRF SSWLSDTEFY ASDHQVNKEK IFPGSGFIEI ANISGNLAGE
QKVSKIKDIV WAHPLSFKKG SQFINTLLKP NGIGTEFKIT SLDDENEQIV HSEGKLFFQN
GNKHLANIEN ISIQKLKEQC ADPHDGSYYY DIFNQVGFNY GLAFKTIQEF YINESFALSR
LKLTDHLLVD SDRFILHPCI VDGALQTVAG LIGQMESVTP HVPFAIDEIE IFRSLPHTCY
AYVQRVEEEA RLQANIKKFN IKIINEAGDV LVKIKNFYVR AFDNTNIDQV KESNSMAFAV
SL
//
