ID A0A023D2N5_ACIMT Unreviewed; 780 AA.
AC A0A023D2N5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Formate dehydrogenase alpha subunit/molybdopterin oxidoreductase {ECO:0000313|EMBL:GAJ28025.1};
GN ORFNames=Amme_012_014 {ECO:0000313|EMBL:GAJ28025.1};
OS Acidomonas methanolica NBRC 104435.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acidomonas.
OX NCBI_TaxID=1231351 {ECO:0000313|EMBL:GAJ28025.1, ECO:0000313|Proteomes:UP000019760};
RN [1] {ECO:0000313|Proteomes:UP000019760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB58 {ECO:0000313|Proteomes:UP000019760};
RX PubMed=24330138; DOI=10.1111/1574-6968.12357;
RA Higashiura N., Hadano H., Hirakawa H., Matsutani M., Takabe S.,
RA Matsushita K., Azuma Y.;
RT "Draft Genomic DNA Sequence of the Facultatively Methylotrophic Bacterium
RT Acidomonas methanolica type strain MB58.";
RL FEMS Microbiol. Lett. 351:9-13(2014).
RN [2] {ECO:0000313|EMBL:GAJ28025.1, ECO:0000313|Proteomes:UP000019760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB58 {ECO:0000313|EMBL:GAJ28025.1,
RC ECO:0000313|Proteomes:UP000019760};
RA Higashiura N., Hadano H., Hirakawa H., Matsutani M., Takabe S.,
RA Matsushita K., Azuma Y.;
RT "Draft genomic DNA sequence of the facultatively methylotrophic bacterium
RT Acidomonas methanolica type strain MB58.";
RL FEMS Microbiol. Lett. 351:9-13(2014).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAJ28025.1}.
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DR EMBL; BAND01000012; GAJ28025.1; -; Genomic_DNA.
DR RefSeq; WP_042056187.1; NZ_BJVB01000013.1.
DR AlphaFoldDB; A0A023D2N5; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000019760; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR CDD; cd02787; MopB_CT_ydeP; 1.
DR CDD; cd02767; MopB_ydeP; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037951; MopB_CT_YdeP.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR InterPro; IPR041953; YdeP_MopB.
DR NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR PIRSF; PIRSF000144; CbbBc; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019760}.
FT DOMAIN 122..416
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 780 AA; 86064 MW; 929FCF46394DEF3B CRC64;
MSETKDTTPD TEPRAEPRYK PYAYPAGGWG AAKATAKVLL EQSVVGKGSR ALLAMNKPGG
FKCPSCAFPD PDREKTLEFC ENGAKALAVE ATKKRVTRAF FAQHTVTALM AQSDYWLEEQ
GRLTEPMRYE PETDRYVPIS WDDAYAMIGA HLRALDHPDE AEFYTSGRTS NEAAFLYSIF
VRQYGTNNFP DCSNMCHEPT SRGLPHAIGV GKGTIVMADF DHAEAIFIFG QNTGTNSPRM
MTNLVDARKR GVPVVIVNPM PERALIRFAE PQDPVQMATF GSTAIASEFV HVRIGGDLAF
VKGMVKAIFE RAAAGEDVLD RAFLAEHTHG MEAWRDEILA LDWEDITRVS GVGEEQIRRA
ADIYVRSNAT VLCFGMGITQ HQNGARMIQQ LAALLMLRGN FGKPGAGIAP IRGHSNVQGD
RTVGIDEKPG AAYLDRVREV FGFEPPRAWG HHVVESVEAM IAGRARVFIG LGGNFIHAIP
ETALAYEAMR RLNLTVGIAT KLNRGHLVHG RDALILPVIA RSEIDRQATG EQFVTIEDAM
SNVTSSRGVL EPASPDLRSE VEIVCRIARA TLPESRIPWE SYIGDYGLIR EKIAEIYPAI
YADFPEKIKN PKGFHLDIPP RRRVWNTPTG KANFLLLPGL HVDDIVTDAA MLRLSTIRSH
DQYNTTIYSN SDRYRGIYND RMVLFLSKAE REARGLPELA KVALETISTD GITRRVEGLT
IVDYPMPRGS VAGYYPELNP LLPLTHFDEI SGTPAAKSIP VRIVPLTEAA EETATKTEAA
//
