ID A0A023D7A6_ACIMT Unreviewed; 1002 AA.
AC A0A023D7A6;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=type I site-specific deoxyribonuclease {ECO:0000256|ARBA:ARBA00012654};
DE EC=3.1.21.3 {ECO:0000256|ARBA:ARBA00012654};
GN ORFNames=Amme_100_015 {ECO:0000313|EMBL:GAJ30052.1};
OS Acidomonas methanolica NBRC 104435.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acidomonas.
OX NCBI_TaxID=1231351 {ECO:0000313|EMBL:GAJ30052.1, ECO:0000313|Proteomes:UP000019760};
RN [1] {ECO:0000313|Proteomes:UP000019760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB58 {ECO:0000313|Proteomes:UP000019760};
RX PubMed=24330138; DOI=10.1111/1574-6968.12357;
RA Higashiura N., Hadano H., Hirakawa H., Matsutani M., Takabe S.,
RA Matsushita K., Azuma Y.;
RT "Draft Genomic DNA Sequence of the Facultatively Methylotrophic Bacterium
RT Acidomonas methanolica type strain MB58.";
RL FEMS Microbiol. Lett. 351:9-13(2014).
RN [2] {ECO:0000313|EMBL:GAJ30052.1, ECO:0000313|Proteomes:UP000019760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB58 {ECO:0000313|EMBL:GAJ30052.1,
RC ECO:0000313|Proteomes:UP000019760};
RA Higashiura N., Hadano H., Hirakawa H., Matsutani M., Takabe S.,
RA Matsushita K., Azuma Y.;
RT "Draft genomic DNA sequence of the facultatively methylotrophic bacterium
RT Acidomonas methanolica type strain MB58.";
RL FEMS Microbiol. Lett. 351:9-13(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage of DNA to give random double-stranded
CC fragments with terminal 5'-phosphates, ATP is simultaneously
CC hydrolyzed.; EC=3.1.21.3; Evidence={ECO:0000256|ARBA:ARBA00000851};
CC -!- SIMILARITY: Belongs to the HsdR family.
CC {ECO:0000256|ARBA:ARBA00008598}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAJ30052.1}.
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DR EMBL; BAND01000099; GAJ30052.1; -; Genomic_DNA.
DR RefSeq; WP_042060605.1; NZ_BJVB01000014.1.
DR AlphaFoldDB; A0A023D7A6; -.
DR OrthoDB; 9758243at2; -.
DR Proteomes; UP000019760; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1570.50; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR007409; Restrct_endonuc_type1_HsdR_N.
DR InterPro; IPR040980; SWI2_SNF2.
DR PANTHER; PTHR42927; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42927:SF1; HELICASE SUPERFAMILY 1 AND 2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04313; HSDR_N; 1.
DR Pfam; PF18766; SWI2_SNF2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000313|EMBL:GAJ30052.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019760};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT DOMAIN 308..503
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
SQ SEQUENCE 1002 AA; 113921 MW; 0796AA1F7D23B973 CRC64;
MNYEQPSTSH PYAKGFSEDT VHREEVLEVH LCKALLERQG YRPRRPEDYD RTSALDKTLV
IEFVKATQPD EWAKLESHYG PSAEAEFFKQ LEQGLKQRGT LDVLRNGLKL VPNLKFFLAA
FKPASGVNPA LVTLFESNIL SVINQLRYSV KSENAIDVGL FVNGLPVATL ELKNTLTGQN
FRHAERQYRH DRAPANEPLL TFKRGALVHF AVDQDNVSMT TRLQNGKTRF LPFNRGHDGG
AGNPDIEGEF RVAYLWADQP EGRAIFSRDI LLDIIGRFLH LDGTNGKEAL IFPRFHQIDA
VLKMLAHARV SGSGSNYLIQ HSAGSGKSNT IAWTAHRLVT LHDPSDQPIF DTAIVVTDRV
VLDRQLQNTI AQFEQTPGVV RKIDGTSRQL KAAIEGQAKI IITTIQKFST DHLRVISGQG
TRRFAVLIDE AHGSQSGKSA QALSDALSRD EEAGTPDEIE DLIAEYQRQR GPQANISYFA
FTATPRNVTL ERFGTVGADG LPHPFHLYSM RQAIEEGFIL DVLQNYMTYK AYYALEKTID
DDPELDTRRA QRKVARFAAL HPTALSQKVE VMVEHFQRHV RPELDGQAKA MIVTSSRESA
LRYYFALKTY IEDKGYRDLK ALVAFSGELH VDGNTYTEAE LNGFGEGELP KRFDTPEYQI
LIVAEKYQTG FDQPKLSGMY IDKKLAGLQA VQTLSRLNRI YQGKERTFIL DFQNTTDDIK
EAFRPFYEVS SLEAVSDKNQ IYQLETRIRT FGYLDSSEIE RFATTFFKGT LSTQDRVTLE
SLVRNAVARF EAEDDEGRQE EFRQLLRSYK RFYSFVAQIV RLGDTSLEKL YAYTDWLDRM
LPNREQPPEV EITDEMLRLR AFRVQQKEAG SASLAAGDAV PLTAISEFGA KPYTEDEAKA
LSEIVRSFND RHGTQFTEED FIRLEQVKRK ALDEEMAAVL RNNPPDVSRP TFVRRLLEET
IKQYQRDSSL QSIIMTNAED RDRIFNHLFS RALREVRETP SP
//
