ID A0A023DC72_9BACI Unreviewed; 740 AA.
AC A0A023DC72;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=kinE {ECO:0000313|EMBL:GAJ38903.1};
GN ORFNames=GCA01S_010_00300 {ECO:0000313|EMBL:GAJ38903.1};
OS Parageobacillus caldoxylosilyticus NBRC 107762.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Parageobacillus.
OX NCBI_TaxID=1220594 {ECO:0000313|EMBL:GAJ38903.1, ECO:0000313|Proteomes:UP000023561};
RN [1] {ECO:0000313|EMBL:GAJ38903.1, ECO:0000313|Proteomes:UP000023561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 107762 {ECO:0000313|EMBL:GAJ38903.1,
RC ECO:0000313|Proteomes:UP000023561};
RA Hosoyama A., Hosoyama Y., Katano-Makiyama Y., Tsuchikane K., Ohji S.,
RA Ichikawa N., Yamazoe A., Fujita N.;
RT "Whole genome shotgun sequence of Geobacillus caldoxylosilyticus NBRC
RT 107762.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAJ38903.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BAWO01000010; GAJ38903.1; -; Genomic_DNA.
DR RefSeq; WP_042407478.1; NZ_BAWO01000010.1.
DR AlphaFoldDB; A0A023DC72; -.
DR OrthoDB; 9815750at2; -.
DR Proteomes; UP000023561; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 4.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF57; SPORULATION KINASE E; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF13426; PAS_9; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:GAJ38903.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000023561};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 30..87
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 151..221
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 272..327
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 392..462
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 524..730
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 10..37
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 740 AA; 85832 MW; 1DF40FD87AED2BEF CRC64;
MSRNLSPREE KNVVVDVRLL EEENRRLKER LNSYSIIFER SLDAIVIFNK HGEFVDVNEA
ACKLFEMDKC ELIGKKLSMF LELVPPDILM FQQSMLHKFG SFSDELLIKL ANGKVKHIEF
SMKKDAFNEY DLVIMRDISA HKALERERIM HEFLFKDVFN RAVDSIVIFD EFGRFIDVNP
AFCMSLNLEK AKLLNLSFQQ FIAKEDVDDF VRLLAELKEK GTAKGELSLV RLDGTVKMFE
LTTTSNVYSG FYMAIMRDVT DRKNMEIKLQ KSEERFRAIF EQAHEAILIW DDYGYILNAN
RAASRTFELP LNLLVRKNLL DFLDHNDEKV KRIFAEFRKK GEIRDELTFH MPNGEDKQLE
FTMKKGAIDG YHLTIFRNVT ERRKIERELR ESEQKFRSIF DHAMDGILLW GQGYRILDVN
PIACEIFQAG KEQLLHRPIT EFIPEKARKH FRKLIQQSER VGEAYAEVDF SNDGKQKIIE
FALKKEIIPG VGMMMLRDIT ERKEMELQLR KSDTLNVVGE LAAGIAHEIR NPMTALKGFI
QLLQGSIKED YSMYFNVIMS ELKRIESIIT EFLVLAKPQA IQYQQNDICK IMQDTIDLIN
VQAMMHSVQI IADFAPQLPP IYCEPNQLKQ VFINILKNAI EVMPKGGDVT VRIRQSDDNH
IRISITDQGC GIPKDKIKKL GEPFYTTKER GTGLGLMVSY KIIEEHQGKI DVESEVGVGT
TFHITLPIKR VEKEDDHDEI
//
