ID A0A023EIJ7_AEDAL Unreviewed; 184 AA.
AC A0A023EIJ7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Nuclear transcription factor Y subunit beta {ECO:0000256|ARBA:ARBA00015277};
DE AltName: Full=CAAT box DNA-binding protein subunit B {ECO:0000256|ARBA:ARBA00029965};
DE AltName: Full=Nuclear transcription factor Y subunit B {ECO:0000256|ARBA:ARBA00031126};
GN ORFNames=RP20_CCG011558 {ECO:0000313|EMBL:KXJ75515.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:JAC08766.1};
RN [1] {ECO:0000313|EMBL:JAC08766.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Reproductive organs {ECO:0000313|EMBL:JAC08766.1};
RX PubMed=24945155;
RA Boes K.E., Ribeiro J.M., Wong A., Harrington L.C., Wolfner M.F.,
RA Sirot L.K.;
RT "Identification and characterization of seminal fluid proteins in the Asian
RT tiger mosquito, Aedes albopictus.";
RL PLoS Negl. Trop. Dis. 8:E2946-E2946(2014).
RN [2] {ECO:0000313|EMBL:KXJ75515.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ75515.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ75515.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [3] {ECO:0000313|EMBL:KXJ75515.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ75515.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ75515.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC box motif found in the promoters of its target genes. NF-Y can function
CC as both an activator and a repressor, depending on its interacting
CC cofactors. {ECO:0000256|ARBA:ARBA00025263}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFYB/HAP3 subunit family.
CC {ECO:0000256|ARBA:ARBA00009053}.
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DR EMBL; GAPW01004832; JAC08766.1; -; mRNA.
DR EMBL; KQ562597; KXJ75515.1; -; Genomic_DNA.
DR RefSeq; XP_019528366.1; XM_019672821.1.
DR AlphaFoldDB; A0A023EIJ7; -.
DR STRING; 7160.A0A023EIJ7; -.
DR VEuPathDB; VectorBase:AALC636_038561; -.
DR VEuPathDB; VectorBase:AALF011558; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0016602; C:CCAAT-binding factor complex; IEA:InterPro.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR027113; Transc_fact_NFYB/HAP3.
DR InterPro; IPR003956; Transcrpt_fac_NFYB/HAP3_CS.
DR PANTHER; PTHR11064; CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED; 1.
DR PANTHER; PTHR11064:SF9; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR PRINTS; PR00615; CCAATSUBUNTA.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00685; NFYB_HAP3; 1.
PE 2: Evidence at transcript level;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 41..105
FT /note="Transcription factor CBF/NF-Y/archaeal histone"
FT /evidence="ECO:0000259|Pfam:PF00808"
SQ SEQUENCE 184 AA; 20720 MW; 8E4684E63964162F CRC64;
MSSSLQSAYF GQDEIDGLNS DDSGAEHLHK VGVPLREQDR FLPIANITKI MKKGIPSNGK
IAKDARECVQ ECVSEFISFI TSEASERCHL EKRKTINGED ILCAMYTLGF DNYCEPLKLY
LTKYRDSIKA ERSSPEQTPE HQQQYETIDQ DFRSIQPSNS NVAVSGNVIY QGSDGGYYLK
SNNF
//
