ID A0A023ERE0_AEDAL Unreviewed; 345 AA.
AC A0A023ERE0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=E3 ubiquitin-protein ligase MARCHF5 {ECO:0000256|ARBA:ARBA00040151};
DE AltName: Full=Membrane-associated RING finger protein 5 {ECO:0000256|ARBA:ARBA00043185};
DE AltName: Full=Membrane-associated RING-CH protein V {ECO:0000256|ARBA:ARBA00043044};
DE AltName: Full=RING-type E3 ubiquitin transferase MARCHF5 {ECO:0000256|ARBA:ARBA00043231};
GN ORFNames=RP20_CCG011845 {ECO:0000313|EMBL:KXJ75370.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:JAC11234.1};
RN [1] {ECO:0000313|EMBL:JAC11234.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Reproductive organs {ECO:0000313|EMBL:JAC11234.1};
RX PubMed=24945155;
RA Boes K.E., Ribeiro J.M., Wong A., Harrington L.C., Wolfner M.F.,
RA Sirot L.K.;
RT "Identification and characterization of seminal fluid proteins in the Asian
RT tiger mosquito, Aedes albopictus.";
RL PLoS Negl. Trop. Dis. 8:E2946-E2946(2014).
RN [2] {ECO:0000313|EMBL:KXJ75370.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ75370.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ75370.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [3] {ECO:0000313|EMBL:KXJ75370.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ75370.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ75370.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GAPW01002364; JAC11234.1; -; mRNA.
DR EMBL; KQ562662; KXJ75370.1; -; Genomic_DNA.
DR RefSeq; XP_019538422.1; XM_019682877.1.
DR AlphaFoldDB; A0A023ERE0; -.
DR STRING; 7160.A0A023ERE0; -.
DR VEuPathDB; VectorBase:AALC636_010506; -.
DR VEuPathDB; VectorBase:AALF011845; -.
DR VEuPathDB; VectorBase:AALFPA_079208; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16701; RING_CH-C4HC3_MARCH5; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011016; Znf_RING-CH.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46283:SF2; AT07234P-RELATED; 1.
DR PANTHER; PTHR46283; E3 UBIQUITIN-PROTEIN LIGASE MARCH5; 1.
DR Pfam; PF12906; RINGv; 1.
DR SMART; SM00744; RINGv; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51292; ZF_RING_CH; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..93
FT /note="RING-CH-type"
FT /evidence="ECO:0000259|PROSITE:PS51292"
FT REGION 319..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 345 AA; 37667 MW; 345D5B5CB87BD410 CRC64;
MASTQGATAA AIAESIAAIN SGPAQEGDER YCWVCFATDE DDKWAPWVQP CNCRGATKWV
HQSCLQRWVD EKQKGNTFKR VSCPQCQSEY IIVLPSMGAL ANVLEGIDTL IKRISPFLTA
GVIVGSVYWT AVTYGAVTVL QTVGYEEGLA LMERAEPIVL LIGLPMVPVG LILGRMIRWE
EFILRFLQTK SFSVRKFPML SLLLPISNMD YDPLYAGSSL AGGGPGGTPP AAPANPLPPG
TVVTSDPLSA TRVLCGALLL PTVSSIVGRV FFDSIRNNFQ RVLVGGFAFV VVKGVLKIYF
KQKQFNRKKQ RRILDYTEEN KQKYGVGHSH QPAQGQGQPG HRHGP
//
