ID A0A023ESX3_AEDAL Unreviewed; 479 AA.
AC A0A023ESX3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN ORFNames=RP20_CCG013216 {ECO:0000313|EMBL:KXJ74644.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:JAC12392.1};
RN [1] {ECO:0000313|EMBL:JAC12392.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Reproductive organs {ECO:0000313|EMBL:JAC12392.1};
RX PubMed=24945155;
RA Boes K.E., Ribeiro J.M., Wong A., Harrington L.C., Wolfner M.F.,
RA Sirot L.K.;
RT "Identification and characterization of seminal fluid proteins in the Asian
RT tiger mosquito, Aedes albopictus.";
RL PLoS Negl. Trop. Dis. 8:E2946-E2946(2014).
RN [2] {ECO:0000313|EMBL:KXJ74644.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ74644.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ74644.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [3] {ECO:0000313|EMBL:KXJ74644.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ74644.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ74644.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001831};
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; GAPW01001206; JAC12392.1; -; mRNA.
DR EMBL; KQ563008; KXJ74644.1; -; Genomic_DNA.
DR RefSeq; XP_019526378.1; XM_019670833.2.
DR AlphaFoldDB; A0A023ESX3; -.
DR STRING; 7160.A0A023ESX3; -.
DR GeneID; 109398460; -.
DR KEGG; aalb:109398460; -.
DR VEuPathDB; VectorBase:AALC636_003616; -.
DR VEuPathDB; VectorBase:AALF013216; -.
DR VEuPathDB; VectorBase:AALFPA_044910; -.
DR OMA; NPKMTAI; -.
DR OrthoDB; 5486434at2759; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR21432:SF20; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR21432; ACETYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 2: Evidence at transcript level;
KW Hydrolase {ECO:0000313|EMBL:JAC12392.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989}.
FT DOMAIN 51..216
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 314..468
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 479 AA; 51808 MW; 1E7A9B602F324266 CRC64;
MMSSLALRFA PRFGKSTAAA VASSSSQQKF NTYYTYSNQI SQPLERKPTY TTAEEAVKCI
KSGDVVFVQG AAATPIHVLD AMTKHGKENN LRDITVVHMH TEGPASYCAP DCKDIFRSKS
LFMGGNVRAA VADGRGDAVP IFLHEIPILF RRKLIQPDVA IVSVSPPDNH GYGTLGTSVD
CVRAALENSK VIIAQVNKQM PRTFGDSIIH ESHFDAAVNV DIPLPEHGGK GMSDTETMIG
KLIAENLVED GATLQMGIGN IPDAVLNALH NHKDLGIHSE MFAGGVVDLV KKGCVTNDKK
TYHRGRIVGS FLIGTKKLYD FVDNNPFIEM LEINYVNNVG IIARNPKMTA INSAIEVDLT
GQVCADSIGT RMYSGFGGQV DFIRGAAEGF DGKGKPIIAL PSITNKGQSK IVPTLKPGAG
VVTSRAHVHY VVTENGIANL FGKSLRQRAY ELIQIAHPDH REALEKAAFE RLKTMPSPN
//
