ID A0A023X5Z1_9ACTN Unreviewed; 256 AA.
AC A0A023X5Z1;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=cAMP-binding proteins-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase {ECO:0000313|EMBL:AHY47763.1};
GN ORFNames=RradSPS_2480 {ECO:0000313|EMBL:AHY47763.1};
OS Rubrobacter radiotolerans.
OC Bacteria; Actinomycetota; Rubrobacteria; Rubrobacterales; Rubrobacteraceae;
OC Rubrobacter.
OX NCBI_TaxID=42256 {ECO:0000313|EMBL:AHY47763.1, ECO:0000313|Proteomes:UP000025229};
RN [1] {ECO:0000313|EMBL:AHY47763.1, ECO:0000313|Proteomes:UP000025229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSPS-4 {ECO:0000313|EMBL:AHY47763.1,
RC ECO:0000313|Proteomes:UP000025229};
RA Egas C.C., Barroso C.C., Froufe H.J.C., Pacheco J.J., Albuquerque L.L.,
RA da Costa M.M.S.;
RT "Complete genome sequence of the Radio-Resistant Rubrobacter radiotolerans
RT RSPS-4.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP007514; AHY47763.1; -; Genomic_DNA.
DR RefSeq; WP_038683051.1; NZ_CP007514.1.
DR AlphaFoldDB; A0A023X5Z1; -.
DR STRING; 42256.RradSPS_2480; -.
DR KEGG; rrd:RradSPS_2480; -.
DR eggNOG; COG0664; Bacteria.
DR HOGENOM; CLU_075053_3_2_11; -.
DR OrthoDB; 9812325at2; -.
DR Proteomes; UP000025229; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF74; REGULATORY PROTEIN CYSR HOMOLOG; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AHY47763.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000025229};
KW Transferase {ECO:0000313|EMBL:AHY47763.1}.
FT DOMAIN 25..146
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 160..233
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 256 AA; 28938 MW; 2DC1A8DF9178563C CRC64;
MEKNGEHLER SEPGEEARLL SLVDIFDGLE PREVPDFVRE CASVAVRKGE VFSTPSDPPE
KALFILKRGR VRVFRKGASG REFTLSVLDG GTVFGELDPT ERRPRRSYAQ AMEPSEVVPL
SREDVERLIL EKPRVGLRLV NLLFERLALH EQRLEDLGLK EVPARLANVL QELIESQGIR
SGSVYKLPTH YTHRHLATMI GANREAVTRA FKVLREYGVV ETHRRNIQVR DFDLLERAGE
DGFLRESDGN GSDGVS
//
