ID A0A023Y5F8_9GAMM Unreviewed; 405 AA.
AC A0A023Y5F8;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Major facilitator transporter {ECO:0000313|EMBL:AHY59902.1};
GN ORFNames=DX03_14695 {ECO:0000313|EMBL:AHY59902.1};
OS Stenotrophomonas rhizophila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Stenotrophomonas.
OX NCBI_TaxID=216778 {ECO:0000313|EMBL:AHY59902.1, ECO:0000313|Proteomes:UP000025222};
RN [1] {ECO:0000313|EMBL:AHY59902.1, ECO:0000313|Proteomes:UP000025222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14405 {ECO:0000313|Proteomes:UP000025222};
RA Alavi P., Starcher M.R., Thallinger G., Zachow C., Mueller H., Berg G.;
RT "Is there a border between beneficial and pathogenic bacteria?";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP007597; AHY59902.1; -; Genomic_DNA.
DR RefSeq; WP_038689822.1; NZ_CP007597.1.
DR AlphaFoldDB; A0A023Y5F8; -.
DR STRING; 216778.DX03_14695; -.
DR GeneID; 61477162; -.
DR HOGENOM; CLU_013133_1_2_6; -.
DR Proteomes; UP000025222; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06177; MFS_NHS; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004740; Nuc_H_symport.
DR PANTHER; PTHR23522; BLL5896 PROTEIN; 1.
DR PANTHER; PTHR23522:SF4; NUCLEOSIDE PERMEASE NUPG-RELATED; 1.
DR Pfam; PF03825; Nuc_H_symport; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 203..405
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 405 AA; 43840 MW; 4EF32B7D31E449F9 CRC64;
MMHTMSRLGA MMFLQFFIWG AWFVTLGTYL VQGPLQASAS QVATAFLSQS IGAIVAPFLV
GLIADRYFAA QRILAVLHLA GAVLMWLAST ATDFRMFFAC VMGYMLLFMP TLALANSVAM
RHMQSPEKQF PLVRVAGSVG WIVAGVLIGW LGWEQAHRLE LTFQMAAMAS LALGLYAFTL
PHTPPLAQQR DAGLGQILGL DSLRLLKSRA YLVFFLSSIA ICVPLAFYYN FTNPYLNDLG
VRSAAGLQSL GQVSEVLLML AMPFLFVRLG VKTMLAVGMA AWVVRYVLFA FGDAGSGFSL
LVIGIVLHGI CYDFFFVTGQ IYTDAHAGPA ARSSAQGFIT LATYGVGMLI GTFLSGAVVE
HYTTAAGPDW QKIWLFPAGV ALVVLIAFLL LFRDRPVVAA APSTP
//
