ID A0A023Y7L0_9GAMM Unreviewed; 886 AA.
AC A0A023Y7L0;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DX03_18410 {ECO:0000313|EMBL:AHY60607.1};
OS Stenotrophomonas rhizophila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Stenotrophomonas.
OX NCBI_TaxID=216778 {ECO:0000313|EMBL:AHY60607.1, ECO:0000313|Proteomes:UP000025222};
RN [1] {ECO:0000313|EMBL:AHY60607.1, ECO:0000313|Proteomes:UP000025222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14405 {ECO:0000313|Proteomes:UP000025222};
RA Alavi P., Starcher M.R., Thallinger G., Zachow C., Mueller H., Berg G.;
RT "Is there a border between beneficial and pathogenic bacteria?";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP007597; AHY60607.1; -; Genomic_DNA.
DR RefSeq; WP_038690969.1; NZ_CP007597.1.
DR AlphaFoldDB; A0A023Y7L0; -.
DR STRING; 216778.DX03_18410; -.
DR GeneID; 61477886; -.
DR HOGENOM; CLU_000445_113_2_6; -.
DR Proteomes; UP000025222; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AHY60607.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 394..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 659..876
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 886 AA; 96744 MW; 31EA848D5FF60463 CRC64;
MSDPRTRQAD ALVERLQREA GGKLTVFLGA APGVGKTFSM LSRAHEQLRR GVDVVVGLVE
THGRAETSAL LEGLPQVPLL QRDYQQHVLG EMDLDAVLAR HPALVLVDEL AHRNVPGSRH
ERRWQDVMEL LEAGIDVWTT VNIQHLESLN DVVMRITGVR VSETVPDAVL DRLHDIVLVD
IPPRELIERL QQGKVYVPEQ AAQALQAFFS PANLTALREL AMQEAADRVD SSLRETRAAR
GEGNLPLRRR VLVAIDGGGQ SEYLVRVGRR IAERRDAPWT VVTVQGRRND EATRREIDAA
FALARRLGGE AELLHGSSIA DALLDHAAHN SVSTLILGRT RERPVARMLN RTLTQQLIQR
GAHYEITIIG TPQARARARR TGLSVPSRST GQDTLLALGA TAIACLVALV AERWVGLYDL
SMVFIVAVVM VAARSRTSAA VIAAALCFLA YNFFFIAPRF TFAISARQGV ITVFLFLAAA
LVAGRLASRL RMQVLALRAA NRHANARQAL GRQLTRAASN EEVAQAGREA LEQAMDAPAW
LRIGQDTSTS GSAAPGDTDL AAADWARRHG QPSGRFTDTL AGAEWWFLPL LDGDDRAIGV
AGMRFARNAP RLTPEQRQLA EAMVDDIAQA ALRTQLVADL EKAHVSNETE RLRSALLSSV
SHDLRSPLAA MIGSADSLGS YADAMDAQDR RALLDTILVE GERLDRYIQN LLDMTRLGHE
GLQINRDWIG VDELVGSAAR RLQRYQPEVQ LKLDIPATLA PIWVHPALVE QAVFNVMENA
AKFSPPGAAV EVQARLVEGE LRIDVLDAGP GIPDDERARI FDMFYSVERG DRGRHGTGLG
LTICQGMIGA HGGSVQALPG RDGRGTLIRI TLPLLQPHPA DDHDDP
//
