ID A0A024G062_9STRA Unreviewed; 4667 AA.
AC A0A024G062;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=BN9_009420 {ECO:0000313|EMBL:CCI40158.1};
OS Albugo candida.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Albuginales; Albuginaceae; Albugo.
OX NCBI_TaxID=65357 {ECO:0000313|EMBL:CCI40158.1, ECO:0000313|Proteomes:UP000053237};
RN [1] {ECO:0000313|EMBL:CCI40158.1, ECO:0000313|Proteomes:UP000053237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ac Nc2 {ECO:0000313|EMBL:CCI40158.1,
RC ECO:0000313|Proteomes:UP000053237};
RA Gardiner A., Kemen E., Schultz-Larsen T., MacLean D., Van Oosterhout C.,
RA Jones J.D.G.;
RT "Recombination and specialization in a pathogen metapopulation.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Consists of at least two heavy chains and a number of
CC intermediate and light chains. {ECO:0000256|ARBA:ARBA00011655}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI40158.1}.
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DR EMBL; CAIX01000006; CCI40158.1; -; Genomic_DNA.
DR STRING; 65357.A0A024G062; -.
DR InParanoid; A0A024G062; -.
DR OrthoDB; 312195at2759; -.
DR Proteomes; UP000053237; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR PANTHER; PTHR10676:SF314; CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053237}.
FT DOMAIN 1903..2061
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2574..2724
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2922..3089
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 3239..3259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3422..3470
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 4667 AA; 533409 MW; 8758897CAF21D7D8 CRC64;
MENLFNETLN LSDSKLKIAQ FVSDHSVRVL QIHWIASNMD MAKDLSETHR SSAQFDLNLG
MKYPTGSHLD HNIICFIKRH NSALSEEELF RHQLQIMTIG LKDANPKSGI NMSKYQGYDQ
SDVLDSASEA GNGESNVLSI VYNYIHQSLG PLVQEYAKIH HPPSTQSSAN EATRGLPAIR
RRMKELELAL LQYQQNIEIP EVKLVFHPVI QNAASLIREK GAPIDMETLN LEDKLQDVTF
LNEIQAGVNR WIKEIQKLTK LINEPLPGTS IQEINFWSDL HRALLQTQEL LASPEVEITM
AILKRAKRYL VTVTFSTDHG LNTTIQQVTS VMSLMKEFPI GAILSATDVT QLTEGVLVIF
NHLKKIRVAD EYKLSRLLQF VEIISSDLMQ QIQGLLRAYK LIQMPYDQFQ TLMGSCKELF
TTWHRQVGML YEVTKELSKR RGTMNTDKPA LLSELQMGHA VIEERLLELA DFREQHQRLC
QVIERVLFNA KPGETIDEAN KGEISLDALT DINTAYDQLA SLDLLDVSSD GNDAWNNARR
SYEFCIDRVE GKITTSLISR LSMTSNADEM FRVFSKYNAL FFRPRIRSAV QQFQMQLIEK
VKEDVGRLQA KFRAHYAFSE ASRTSKLRDI PPVSGAIMWA RQIERKLKLI LSRVESVLGA
GWEQHVEGRA LKMAAEAFMS RLNPQLIFDQ WVGELASMPI FDIKNIILNI ITVETAKGPQ
KRLVVAFNHQ IVTLFKEVRN LDWLNFRVPF TLKMIAEDAK SKYPHAMSLD ASLKTYTTAC
QRIQPIFEPL AAGYVKAIRV AIGKTFVRGN EMRWHADGLG EYVSDVVVKA ETLHDKVEEL
IEKCKGINHI LEVLHAAPEM DLDLIRSELA KIQSIVDELS LSDYNNLDIF VSKLNDKLSE
VLAAKLQHVL GLWVELFEAE EARENGQNVS PESTRKWNTA ASVLEVASKT HQIVLRNQVL
SIAPSLDVAR SFWFEQLHQL ISGLCCLPKI QTSSYENVYG PTASLNALMS SSTRRRDASM
RRKEVHFEHI LHGVPKPLVI QAYRAVNNVI TAADAYAATW LHYQTLWDMD AQTAIASLGE
DLCKWQQILL EIKRERSSFD VVTDSKRFGP IVINYQQVQA QVNVKYDAWH NEFISYFADL
LCSKINEFYG IISSKRTQLE SHVLEAATAQ VVSAVTLVQE MKKMRSQWKK TIESFIQGES
LLKRQRYKFN SNWPSLANVE GEWDAFLQLL ERKSTAIDSQ LPQLQTKVMD EKTALENRIS
EAVSDWDSNK PLHGDQSPKS ALEMLVLFDS RFKILQQEWV KMEGALEALE LTLYPGGGLQ
SSLSNIKRVI EEISGLDEVW RNLLSVWVEL EELQETMWSA VQARKIRRQL EEFTEQMRRL
PARVQQYEAF EHFIASIQLK KSINSLLSDL KSDAIRERHW KQILAFLKIT CPFSELTLRN
FWESRIAQHE VELKSLIQAA QGEMALDEFL RQLGEHWNNS QLELVAYQNR CRIVRGWDEI
FAKLEEHLNS LSSMKQSPFY RVFADLALNW EEKLNRVKSI LDAWIDVQRR WVYLEGIFFG
SADIKQQLPK EYMRFQSIDN EFMTMMKRVA QKPQILEVAN IPNLLHTLER QQEMMGNVQR
ALGEYLERQR ATFPRFYFVG DEDLLEIIGN SKEPVHIQRH LSKMFAGIAS LKLSENDANV
IIGMVSREGE EVLFKESICV AEDSRVNIWL RQVEVQMRDT LAHSLTLCYT SCPESTQKAS
FIQWISTYPA QIIILATQVR WSNAVEAALT TGGSGALEKL DQVVALADDT LQLLSQQVLL
DITTEMRKKY EQLITEIVHE RSVTLRLSQA QVTDVRDFRW IYHMRYYFNP AEPESSKRLT
IKISDATFPY GFEYLGVGER LVQTPLTERC YLTLTQALDF GLGGNPFGPA GTGKTESVKA
LGAQLGRFVL VFNCDEHFDF QAMGRIFVGL CQVGAWGCFD EFNRLEERVL SAVSQQILAI
QSGVSLLKVR DKESNSTHSN TTPIMVELLG KNVKLHANVG IFVTMNPGYA GRSNLPDNLK
QLFRSIAMTA PDRELIAQVM LFSQGITIAQ SIAAKVVLLF RLCEDQLSKQ PHYDFGLRAL
KSVLISAGHL KRKVMNETRT LVDIEKIEMT ALLGSINDTI LPKLVASDVA VFEALFDGTF
PNIERVHLHD VTLQQTVERI AQSQQLVVHK PWILKILQLQ QVSQLRHGVM LVGPSGTGKT
RAWQVLLASL EANYGMKSEA HVIDPKALSK EHLYGSLDNT TLEWTDGVFT SILRQILNSV
RGECDKRHWI IFDGDVDPEW AENLNSVLDD NRILTLPSGE RLELPSNVWI IMETESLEHA
TLATVSRCGM VWFSEDTIGT HHVVEHNLLR LENGEMAISY SLDAENVVQT TFTYVNAIRE
LISQSDSSVM SLLEVVLDFA MAMKHIMDVT KARLLMSLLS LLNKGLSRIH EYNETHADFM
LNETQIVGLS TKWFIFALVW GFGSSMNSKN RLCLCDHIVE IFGNRLSLPV NGRNTPENSL
LDYEVHFETN EWRNWTQSVP QVDLESHRVL ATDVVVPTVD TVRHVEVLRG WLSQHRPLIL
CGPPGSGKTM TLTSTLSSLP QFDFASLNFS SGTTPELLLK TFSQYCEYKR TPNGMILVPN
SPEKWLVVFC DEINLPEADR YGTQRVITFL RQMIEHGGFW LGSKVCWVTL QRIQFVGACN
PPTDPGRVPL SLRLLRHAPV LLVDFPTTTS LKQIYKTFNR ALLKLTPSLK AYSQPLTECM
VAIYQENQNR FTTELQPHYI YSPRELSRWM RALYEALEPL EFELDIENLV RLTFHEALRL
FMDRLAIFEE QQWCFTTIKE ILRHHFPQTA TSLNAIDHKG QNPILFSSWL SKQYVEVNIE
ELRTHVEARL RVFYEEELNV PLVVFDSVLD HVLRIDRVLR QPLGHLLLVG ESGAGKTVLS
RFVSWMNGMS VFQIKLTSRY TLENFDEDLR VVLKRCGCDG ERICFIFDES NILSSAFLER
MNALLASGEV PGLFEDEEYI SLMHACREAV QRDGGMVENT ESELFRYFTR QVQRNLHVVF
TMNPASGDFQ DRQKTSPALF NRCVVDWFGT WNDRALAQVA QEFTKTLDLP STDRSMLSTQ
AQGILAELLP GQSMNGLREG LTGSIVEVHH ATLQLMQRLR KRHLPFNHIS PRDFLEFIRQ
FVSLYNEKRS LLEDQQLHLN IGVCKLQATH EQVAELQGQL SLKEKELKKN NEEANKKLQQ
MVKEQKDAEE KKRDTEQLAT DLGQQDEEIT KRKQVVEADL AEAEPALLDA QQSVNSIRKS
QLDEIRALAR PPAAIRMTLE AVALMLGETS LDWADLRRFI RRDDFISQIV NFDSEKLTQK
QRNVIRTNYV EKPDEFDYEK VNRASKACGP LFKWVVSQLH FTEILHRIQP LRNEVQSLVD
RSATLREQFQ AAKAMVDELE IRIEKFKQEY ASLINEAQKI SNDMEQVNQK VNRSVALLDS
LLHESERWGS SADGFELQMA TLTGDTLLSA AFLTYIGFLD FQQRKILTQD WRDILQSFGI
HVKDDLSFVD YLSRPQDQLE WQQSELPTDE LCYENAIILQ RFRRFPLIID PSGQANRFIT
QNYARKTNTK ITQTSFLDTS FMKVLASAIR FGTALLVHEV ENIDPVLNPV LNRELYKTGG
RVLIRLAGEE IDYSPDFRLF LITRNPTCRF PPDICSRVTF INFTVTPSSL ESQALSILMK
SEEPEAERKR TSLLKMQGEY QAKLRELEDS LLQQINNVQG NILDDNSVIN SLEAMKAEAA
QITSQVSDTQ VTMKSVEQAT NRYRPLAKAC SKLFFALESM SMVHFLYQFS LEFFLDMLSL
VLGIDGSCEL TGTHTADADV SRLNKLSALL FKVVSSRVSR GLAERDKLMF ALRMAQIYID
LKRDTIKVDG GSMEPTHFDG PTDFEWESLY NKRTLALRSD AIEEELGALM EGPNEQKKWR
QLLRTNLFEN LPSHLKQNAH EWTKFIKHVA PEENIPSGWD QICEIADVSS IRAAFRDLIL
IHYLRPDRVT KAAEKFIDRT FGRDFPWRGE IELQKNVSTD TNARRGILLC STTGYDASSQ
IDGLAAHLNK KLTSVSMGSP EGFDLAEKGL NTALKQGSWL LLRNVHLCPS WLMSLEKKLY
NARTCAHTNF RLFLTSEINP SLPLNLIRLC DVYVFEPPGG MKLSILRSLD ALSDERMDSV
PAERARLFLL LAWFHGLVQE RLRYVPVGWS KAYEFGHSDF RVACDVIDRW VNAEGTSRAH
LSPDQMPWAA IRTTLSQSIY GGRIDNEFDQ VLLETLLETV FTPESYQNTF KLVTDTDYAA
EDVTIAEGRT KAQFMKWVHN LPNSNSPTWL GLAKSAEQML QLQQGEHMVR CLQLVQDVYG
SEEKEDQQEN VSAFSVQSER PKWIVALEKR VSHFLSVLDI QLVTDTAQDF SERLSCCVNR
EVEYGKWCLQ VVRGLLEAIA SVCANQTKPS GEIRMDMHTL SRGSLPSQWK NLYYTPPEIE
IDEWFLDFQQ RLQQANDLCV VDVHQLLTFE KEIWLGGLFF PESFIASTRQ SLAKTLQCSL
DDLFLEVAVD KFNGAPNGFV ACNLRLEGAH WSQDEFYPTE AIYVEVPKLY MRWSPFDCKT
EEHRRIPVYA STRRENVLFT VHAIVNESTY PLCQWHQRSI ALVLSHK
//
