ID A0A024G1V2_9STRA Unreviewed; 699 AA.
AC A0A024G1V2;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=cysteine--tRNA ligase {ECO:0000256|ARBA:ARBA00012832};
DE EC=6.1.1.16 {ECO:0000256|ARBA:ARBA00012832};
DE AltName: Full=Cysteinyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031499};
GN ORFNames=BN9_016020 {ECO:0000313|EMBL:CCI40818.1};
OS Albugo candida.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Albuginales; Albuginaceae; Albugo.
OX NCBI_TaxID=65357 {ECO:0000313|EMBL:CCI40818.1, ECO:0000313|Proteomes:UP000053237};
RN [1] {ECO:0000313|EMBL:CCI40818.1, ECO:0000313|Proteomes:UP000053237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ac Nc2 {ECO:0000313|EMBL:CCI40818.1,
RC ECO:0000313|Proteomes:UP000053237};
RA Gardiner A., Kemen E., Schultz-Larsen T., MacLean D., Van Oosterhout C.,
RA Jones J.D.G.;
RT "Recombination and specialization in a pathogen metapopulation.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI40818.1}.
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DR EMBL; CAIX01000011; CCI40818.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A024G1V2; -.
DR STRING; 65357.A0A024G1V2; -.
DR InParanoid; A0A024G1V2; -.
DR OrthoDB; 2140072at2759; -.
DR Proteomes; UP000053237; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004817; F:cysteine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006423; P:cysteinyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00672; CysRS_core; 1.
DR Gene3D; 1.20.120.1910; Cysteine-tRNA ligase, C-terminal anti-codon recognition domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR HAMAP; MF_00041; Cys_tRNA_synth; 1.
DR InterPro; IPR015803; Cys-tRNA-ligase.
DR InterPro; IPR015273; Cys-tRNA-synt_Ia_DALR.
DR InterPro; IPR024909; Cys-tRNA/MSH_ligase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR032678; tRNA-synt_1_cat_dom.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR NCBIfam; TIGR00435; cysS; 1.
DR PANTHER; PTHR10890:SF3; CYSTEINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR PANTHER; PTHR10890; CYSTEINYL-TRNA SYNTHETASE; 1.
DR Pfam; PF09190; DALR_2; 1.
DR Pfam; PF01406; tRNA-synt_1e; 1.
DR PRINTS; PR00983; TRNASYNTHCYS.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000053237};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 49..399
FT /note="tRNA synthetases class I catalytic"
FT /evidence="ECO:0000259|Pfam:PF01406"
FT DOMAIN 446..506
FT /note="Cysteinyl-tRNA synthetase class Ia DALR"
FT /evidence="ECO:0000259|Pfam:PF09190"
FT REGION 651..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 596..637
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 699 AA; 80455 MW; B30F1F48B28602C7 CRC64;
MTVEDCLSGK QCQPDWHPPR PLHSLIEYWS KHYPLKLYNS LTRTKNHFIP IKGRRVLWYM
CGPTVYDQTH LGHGRTYTCF DYARRIIEDY FGYEVELVMN ITDIDDKIII RAAENGWKQA
FPEKDLPTNT EQRVQIVMEW ASRQSAEENM KRTKDLSQFW EASFLHDMAS LGIKTPTVIT
RVSEYVDDII IFVQGIIKNG FAYESNGSVY FDTNKFSQSS GKAYGKLLPE NVGQTELLAE
GEGSLVTKST VSGNSDKQGA SDFVLWKKSK HGEPFWVSPW GPGRPGWHIE CSAMASSTLQ
RFAEGQIDIH SGGIDLRFPH HDNEIAQSEA YFNFSQWINY FLHTGHLNIE GLKMSKSLKN
FVKIKDALLD HSSRQLRFLF LLHKYNVPME YNDHSMEEAV VVDRFFNEFF QNVKVQLRLL
GMKNAQKWEE RDIQLHDAIV ACKQNVHQAL ADDLNTPQAI LHLQHLAKEV SRYMASSEEH
NKVTLLIRSA ADYVTSIFRI FGLIQSGSDI GFPLTSSSEE AAAVNEETIL TPVLDIFAEF
RDEIRELARS ATTGDIDGKA LAAKILHTCD RVRDDKLPHA GIRLEDRANT KAIWKLANKE
ELLEEQRRKS LEKEKKEEEK RLRMEEAIRK KKEVEEKAKI DPKEMFLAQK EKYSKFDHQG
LPTHDANGEE LSKGQLKKLS KEQAKQRTLY LKYQEAKTL
//
