ID   A0A024GQX1_9STRA        Unreviewed;       775 AA.
AC   A0A024GQX1;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=CBS domain-containing protein {ECO:0000259|Pfam:PF00571};
GN   ORFNames=BN9_104740 {ECO:0000313|EMBL:CCI49192.1};
OS   Albugo candida.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Albuginales; Albuginaceae; Albugo.
OX   NCBI_TaxID=65357 {ECO:0000313|EMBL:CCI49192.1, ECO:0000313|Proteomes:UP000053237};
RN   [1] {ECO:0000313|EMBL:CCI49192.1, ECO:0000313|Proteomes:UP000053237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ac Nc2 {ECO:0000313|EMBL:CCI49192.1,
RC   ECO:0000313|Proteomes:UP000053237};
RA   Gardiner A., Kemen E., Schultz-Larsen T., MacLean D., Van Oosterhout C.,
RA   Jones J.D.G.;
RT   "Recombination and specialization in a pathogen metapopulation.";
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCI49192.1}.
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DR   EMBL; CAIX01000281; CCI49192.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A024GQX1; -.
DR   InParanoid; A0A024GQX1; -.
DR   OrthoDB; 7615at2759; -.
DR   Proteomes; UP000053237; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   Gene3D; 3.10.580.10; CBS-domain; 2.
DR   Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   PANTHER; PTHR45720; CHLORIDE CHANNEL PROTEIN 2; 1.
DR   PANTHER; PTHR45720:SF10; CHLORIDE CHANNEL PROTEIN 2; 1.
DR   Pfam; PF00571; CBS; 1.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   SUPFAM; SSF81340; Clc chloride channel; 1.
PE   4: Predicted;
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053237};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        92..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        135..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        196..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        240..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        278..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        325..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        367..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        417..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        508..527
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          724..767
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|Pfam:PF00571"
SQ   SEQUENCE   775 AA;  85291 MW;  3E84A44E198C3F31 CRC64;
     MKQSVAEDVP SHLRRTGRIE SLAEFQQRVR IQSSVSIEDP QVENLTDSVQ IARDTIADSN
     VYLRRQSTVS SFGPVTPHPI HKSNLRYRQY KILFFLFILG IIGVPVIYSM KRLDAIILSR
     RMRYIDQLRD GGSEYFAWIV HALFFTIVGL LLTQISSAAA GSGVSQMKTI LTGIDPSFYL
     PGYFDASTLI AKMGGLVCAV GAGLVVGTEG ANVHIMSIIT HHLLRLGIFE NLGERLNMRL
     QFLAAACAVG VAATFSSPIG GVLFSMEVTS TYYLISNYLK AFISSVSGAL VLKVLLTLTF
     ADAKEANSSI LMTSFPPQPY TIQEIPLYML LGLCIGVIAT GMLWLVRVIA IKRTEFRQMK
     SVKMQFFIRW VDPMLVAVLC ASATYLPGKF TQIGRMSEIV ILFTPTELPE SWQLISKYYA
     CTIVCAIYVI LLPLCITLKL PTGIWLPTFI AGAAFGRCFG EFVKSVFPTR GVIPGTYALA
     GAAAFGGAST KTISVAVITL EITGAMQLML PIFCAVLVSI GVVRVLGELS VYDTLLFISK
     LPYLPTLRID SSKAVGDVME PLAVYVTRIT TISKLLLVVQ RMPGQDVPVL RDEETRMLLG
     VVSTSQLRLF IHKYYSEHEL PDVEVDLGEA PTLIAGHPSG SFGFNFTRNF AGGLNGTLSY
     DQLHNALTTK TAPAGDLYRL PFILDDHRML NLLTRDWTTN KKQLLDRKVK LNHHNGCFIK
     PLAVTISSTT PLDDLHMIFT MFRCDHCFVC DQGALVGVVT TKALLQAGNG TKHME
//