ID A0A024HE85_PSEKB Unreviewed; 377 AA.
AC A0A024HE85;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Alkane 1-monooxygenase 2 {ECO:0000313|EMBL:CDF83375.1};
DE EC=1.14.15.3 {ECO:0000313|EMBL:CDF83375.1};
GN Name=alkB2 {ECO:0000313|EMBL:CDF83375.1};
GN ORFNames=PKB_2028 {ECO:0000313|EMBL:CDF83375.1};
OS Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1301098 {ECO:0000313|EMBL:CDF83375.1, ECO:0000313|Proteomes:UP000025241};
RN [1] {ECO:0000313|EMBL:CDF83375.1, ECO:0000313|Proteomes:UP000025241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B13 {ECO:0000313|EMBL:CDF83375.1,
RC ECO:0000313|Proteomes:UP000025241};
RA Linke B.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDF83375.1, ECO:0000313|Proteomes:UP000025241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B13 {ECO:0000313|EMBL:CDF83375.1,
RC ECO:0000313|Proteomes:UP000025241};
RA Miyazaki R., Bertelli C., Falquet L., Robinson-Rechavi M., Gharib W.,
RA Roy S., Van der Meer J.R.;
RT "Genome sequence of the 3-chlorobenzoate degrading bacterium Pseudomonas
RT knackmussii B13 shows multiple evidence for horizontal gene transfer.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family. AlkB
CC subfamily. {ECO:0000256|ARBA:ARBA00010823}.
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DR EMBL; HG322950; CDF83375.1; -; Genomic_DNA.
DR RefSeq; WP_043251315.1; NZ_HG322950.1.
DR AlphaFoldDB; A0A024HE85; -.
DR STRING; 1301098.PKB_2028; -.
DR KEGG; pkc:PKB_2028; -.
DR PATRIC; fig|1301098.3.peg.2017; -.
DR eggNOG; COG3239; Bacteria.
DR HOGENOM; CLU_044462_1_0_6; -.
DR OrthoDB; 4759734at2; -.
DR Proteomes; UP000025241; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0018685; F:alkane 1-monooxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd03512; Alkane-hydroxylase; 1.
DR InterPro; IPR033885; AlkB/XylM.
DR InterPro; IPR005804; FA_desaturase_dom.
DR PANTHER; PTHR38674; ALKANE 1-MONOOXYGENASE 1; 1.
DR PANTHER; PTHR38674:SF1; ALKANE 1-MONOOXYGENASE 1; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Iron {ECO:0000256|ARBA:ARBA00023004}; Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033, ECO:0000313|EMBL:CDF83375.1};
KW Oxidoreductase {ECO:0000313|EMBL:CDF83375.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000025241};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 114..343
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 377 AA; 43477 MW; 30AF0E97B997F4D0 CRC64;
MFAFLPPAWM LSLKKAGYWI WLVPVFGIPV SYWWSYGSDH PNAWGWFVIS VVFLVIPILD
AIVGRDPANP DETTEVPVLE REGYYRFLSL LTVPLLLGML VYGGWVLAHY EAWNWVGKLG
WILSVGTVMG AIGITVSHEL IHKDPQLEQM AGGLLLAAVC YAGFKVEHVR GHHVNVSTPD
DASSSRYDQS LYAFLPHAYK HNFLNAWRLE AQRLKRKGLP ALHWRNELIW WYVISALFLV
GFSVAFGWIG AVYFLGQSAM AFTLLEIVNY VEHYGLHRRR LDDGRYERTT HEHSWNSNFL
LTNLFLFHLQ RHSDHHAYAK RRYQVLRHYD ASPQLPNGYA GMIVLALFPP LWRAVMNPRV
RAYYAGEEYQ LSDTQRA
//
