ID A0A024HL80_PSEKB Unreviewed; 288 AA.
AC A0A024HL80;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Rhomboid family intramembrane serine protease {ECO:0008006|Google:ProtNLM};
GN ORFNames=PKB_3846 {ECO:0000313|EMBL:CDF85183.1};
OS Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1301098 {ECO:0000313|EMBL:CDF85183.1, ECO:0000313|Proteomes:UP000025241};
RN [1] {ECO:0000313|EMBL:CDF85183.1, ECO:0000313|Proteomes:UP000025241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B13 {ECO:0000313|EMBL:CDF85183.1,
RC ECO:0000313|Proteomes:UP000025241};
RA Linke B.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDF85183.1, ECO:0000313|Proteomes:UP000025241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B13 {ECO:0000313|EMBL:CDF85183.1,
RC ECO:0000313|Proteomes:UP000025241};
RA Miyazaki R., Bertelli C., Falquet L., Robinson-Rechavi M., Gharib W.,
RA Roy S., Van der Meer J.R.;
RT "Genome sequence of the 3-chlorobenzoate degrading bacterium Pseudomonas
RT knackmussii B13 shows multiple evidence for horizontal gene transfer.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase S54 family.
CC {ECO:0000256|ARBA:ARBA00009045}.
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DR EMBL; HG322950; CDF85183.1; -; Genomic_DNA.
DR RefSeq; WP_043253539.1; NZ_HG322950.1.
DR AlphaFoldDB; A0A024HL80; -.
DR STRING; 1301098.PKB_3846; -.
DR KEGG; pkc:PKB_3846; -.
DR PATRIC; fig|1301098.3.peg.3856; -.
DR eggNOG; COG0705; Bacteria.
DR HOGENOM; CLU_058989_1_0_6; -.
DR OrthoDB; 9778341at2; -.
DR Proteomes; UP000025241; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR Gene3D; 3.30.70.2080; -; 1.
DR Gene3D; 1.20.1540.10; Rhomboid-like; 1.
DR InterPro; IPR031976; NRho.
DR InterPro; IPR038244; NRho_sf.
DR InterPro; IPR022764; Peptidase_S54_rhomboid_dom.
DR InterPro; IPR035952; Rhomboid-like_sf.
DR PANTHER; PTHR43731:SF26; RHOMBOID DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43731; RHOMBOID PROTEASE; 1.
DR Pfam; PF16733; NRho; 1.
DR Pfam; PF01694; Rhomboid; 1.
DR SUPFAM; SSF144091; Rhomboid-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000025241};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..67
FT /note="Rhomboid protease N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16733"
FT DOMAIN 137..278
FT /note="Peptidase S54 rhomboid"
FT /evidence="ECO:0000259|Pfam:PF01694"
SQ SEQUENCE 288 AA; 31403 MW; 4356E72D9F9BB97D CRC64;
MTAVVAMRLP LSEDLAGFVG LLQRLNVPFR VSEESGEQVL WVPNEELAEQ VRSLYQRYPQ
GDPELTAPAW KPQRGPGFLE QLRLSKMTAA VLLVTFVVAA VTLLGANPTT LRWFTFQDFQ
LVGSDHVMFI PLADGLAAGQ WWRLLTPMLL HFGWLHLAMN AMWYWELGRR IEYRQGGLML
LGLSLGVGLV SNVVQYMVSG PSLFGGLSGV LYGLLGHCWI FQLLAPTPAY RLPKGVVGMM
LIWLLVCLSG VIDLLGFGSI ANGAHVGGLV VGCATGALGG LLARRKGM
//
