ID   A0A024JX11_9MYCO        Unreviewed;       469 AA.
AC   A0A024JX11;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=amidase {ECO:0000256|ARBA:ARBA00012922};
DE            EC=3.5.1.4 {ECO:0000256|ARBA:ARBA00012922};
GN   ORFNames=BN973_02250 {ECO:0000313|EMBL:CDO87892.1};
OS   Mycobacterium triplex.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium simiae complex.
OX   NCBI_TaxID=47839 {ECO:0000313|EMBL:CDO87892.1};
RN   [1] {ECO:0000313|EMBL:CDO87892.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44626 {ECO:0000313|EMBL:CDO87892.1};
RX   PubMed=24874681; DOI=10.1128/genomeA.00499-14;
RA   Sassi M., Croce O., Robert C., Raoult D., Drancourt M.;
RT   "Draft Genome Sequence of Mycobacterium triplex DSM 44626.";
RL   Genome Announc. Announc.2:e00499-e00414(2014).
RN   [2] {ECO:0000313|EMBL:CDO87892.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 44626 {ECO:0000313|EMBL:CDO87892.1};
RA   Xu Y.W., Yang Q.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a monocarboxylic acid amide + H2O = a monocarboxylate +
CC         NH4(+); Xref=Rhea:RHEA:12020, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:35757, ChEBI:CHEBI:83628; EC=3.5.1.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00001311};
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DR   EMBL; HG964446; CDO87892.1; -; Genomic_DNA.
DR   RefSeq; WP_036468070.1; NZ_LQPY01000034.1.
DR   AlphaFoldDB; A0A024JX11; -.
DR   STRING; 47839.BN973_02250; -.
DR   eggNOG; COG0154; Bacteria.
DR   HOGENOM; CLU_009600_0_4_11; -.
DR   OrthoDB; 5175573at2; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR   InterPro; IPR000120; Amidase.
DR   InterPro; IPR020556; Amidase_CS.
DR   InterPro; IPR023631; Amidase_dom.
DR   InterPro; IPR036928; AS_sf.
DR   PANTHER; PTHR11895:SF180; AMIDASE AMIC-RELATED; 1.
DR   PANTHER; PTHR11895; TRANSAMIDASE; 1.
DR   Pfam; PF01425; Amidase; 1.
DR   SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
DR   PROSITE; PS00571; AMIDASES; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          33..450
FT                   /note="Amidase"
FT                   /evidence="ECO:0000259|Pfam:PF01425"
SQ   SEQUENCE   469 AA;  50810 MW;  FD43817876BE5075 CRC64;
     MRRVHAFGDD ALGDLDATAL SEAIRASWVG RTEVVEAAIA RTEAVNPILN GLAYKAFEQA
     RARAAATPSS AFFSGVPTFL KDNVDVAGQP TMRGADAWAP RNAVADGEFT QLYLGTGPTS
     LGKTQMSEFG FSAAAEHPRL GPVRNPWDTD RTAGASSSGS GAFVAAGVVP IAHANDGGGS
     IRIPAACNGI VGLKPSRGRL PLDADLRRMP VGIVANGVLT RSVRDTAAFY REAERIWRNA
     KLAPIGDVTG PGRQRLRIAV ATGSVRRECG PQLRELTLKT AGVLEELGHR VEHIDHHPVP
     DSFVDDFILY WGFLALMQVR TGRRVFGNTF DRTRLDALTL GLERHTGRNL HRLPGVIWRL
     RSMRRRSAEF YQTYDALLTP TLADLTPRVG HLAPTEYQQV MDRLIDWVAF TPLQNVTGDP
     AISLPLAQSA DGMPVGMMLA ADLGQDALLL ELAYELEQAR PWARIQADG
//