ID A0A024JXN3_9MYCO Unreviewed; 400 AA.
AC A0A024JXN3;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=propanoyl-CoA C-acyltransferase {ECO:0000256|ARBA:ARBA00012352};
DE EC=2.3.1.176 {ECO:0000256|ARBA:ARBA00012352};
DE AltName: Full=Propanoyl-CoA C-acyltransferase {ECO:0000256|ARBA:ARBA00032316};
GN Name=ltp1_1_2 {ECO:0000313|EMBL:CDO88580.1};
GN ORFNames=BN973_02949 {ECO:0000313|EMBL:CDO88580.1};
OS Mycobacterium triplex.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=47839 {ECO:0000313|EMBL:CDO88580.1};
RN [1] {ECO:0000313|EMBL:CDO88580.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44626 {ECO:0000313|EMBL:CDO88580.1};
RX PubMed=24874681; DOI=10.1128/genomeA.00499-14;
RA Sassi M., Croce O., Robert C., Raoult D., Drancourt M.;
RT "Draft Genome Sequence of Mycobacterium triplex DSM 44626.";
RL Genome Announc. Announc.2:e00499-e00414(2014).
RN [2] {ECO:0000313|EMBL:CDO88580.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 44626 {ECO:0000313|EMBL:CDO88580.1};
RA Urmite Genomes U.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; HG964446; CDO88580.1; -; Genomic_DNA.
DR RefSeq; WP_036468942.1; NZ_LQPY01000008.1.
DR AlphaFoldDB; A0A024JXN3; -.
DR STRING; 47839.BN973_02949; -.
DR eggNOG; COG0183; Bacteria.
DR HOGENOM; CLU_035425_4_0_11; -.
DR OrthoDB; 9785768at2; -.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd00829; SCP-x_thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR PANTHER; PTHR42870; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR42870:SF1; NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Transferase {ECO:0000256|RuleBase:RU003557};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 6..196
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 273..376
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
SQ SEQUENCE 400 AA; 41520 MW; 3CD039826706D17F CRC64;
MSSGDVWVVG AAMTKIGRYP DKDVIDLASD AVLGALRDAS IEMSQVQFLA CGNAYESNSG
VAQRLQKQVG QMGIPAYNVF NACATGASAV RLAILAIKAE ECDVALAVGA EQMGKMGLLG
NKGKRGDRKS FVPKGRYGGV LPTEGILGTQ LMPGVFAQAG MEYALQHGVT REQFAMIAVK
NHRNSVRNPY AQYRKEFSLD EVLGAEVIAY PNTLPMCCPT GDGAAAVLVV SDRRLAQLDP
DVRRRAVKIS ASVITTDPWT DSAQVQPDIN TLTRNAAALA YEAAGLGPGD LSLVELHDCF
ATAELLHYDN LGLCPPGGAG DFISSGAADA DGRTPVNVSG GLLSKGHPIG ATGVAGLYEI
ATQLRGEAGD RQVGGANVGL AHVIGLGSAC GIHILEKGAA
//
