ID A0A024K0G7_9MYCO Unreviewed; 333 AA.
AC A0A024K0G7;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=RNA polymerase sigma factor {ECO:0000313|EMBL:CDO89077.1};
GN ORFNames=BN973_03448 {ECO:0000313|EMBL:CDO89077.1};
OS Mycobacterium triplex.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=47839 {ECO:0000313|EMBL:CDO89077.1};
RN [1] {ECO:0000313|EMBL:CDO89077.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44626 {ECO:0000313|EMBL:CDO89077.1};
RX PubMed=24874681; DOI=10.1128/genomeA.00499-14;
RA Sassi M., Croce O., Robert C., Raoult D., Drancourt M.;
RT "Draft Genome Sequence of Mycobacterium triplex DSM 44626.";
RL Genome Announc. Announc.2:e00499-e00414(2014).
RN [2] {ECO:0000313|EMBL:CDO89077.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 44626 {ECO:0000313|EMBL:CDO89077.1};
RA Xu Y.W., Yang Q.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641}.
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DR EMBL; HG964446; CDO89077.1; -; Genomic_DNA.
DR RefSeq; WP_036469557.1; NZ_LQPY01000029.1.
DR AlphaFoldDB; A0A024K0G7; -.
DR STRING; 47839.BN973_03448; -.
DR eggNOG; COG1595; Bacteria.
DR HOGENOM; CLU_047691_22_1_11; -.
DR OrthoDB; 3211555at2; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30173:SF43; ECF RNA POLYMERASE SIGMA FACTOR SIGI-RELATED; 1.
DR PANTHER; PTHR30173; SIGMA 19 FACTOR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 20..83
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 118..167
FT /note="RNA polymerase sigma factor 70 region 4 type 2"
FT /evidence="ECO:0000259|Pfam:PF08281"
FT REGION 307..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 333 AA; 35982 MW; C3432B555C334C51 CRC64;
MNAPGNLVDL ADLAQRFDAD RQHLRAVAFR LLGSIPDADD AVQSAWLKAS RADGIGEIAN
LTGWFTTITA HEAFDQLRAR KRRAEQPLAD AAELDRLATT AAADEDALLA DSVDSAMLVV
LDRLSPAQRV AFVLHDVFAM PFETIGEVLD RSPAAAKKLA SRARARLHGG SAARPRRPAR
HLEIVEAFLA ASRGGDIAAL LELLAPEVVR RVDRALVPED VAAELRGARE VAEETRRFAR
RARAGVVLLI DGVPGIVIAP RGRAQILLRL GIGADNRIHA IDISADAAEL RRAVLALPGW
LPQADSRPIR YQGHGTRPVG SSETGREREQ DAR
//
