ID   A0A024K4C7_9MYCO        Unreviewed;       381 AA.
AC   A0A024K4C7;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=Thiolase {ECO:0000313|EMBL:CDO90741.1};
GN   ORFNames=BN973_05141 {ECO:0000313|EMBL:CDO90741.1};
OS   Mycobacterium triplex.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium simiae complex.
OX   NCBI_TaxID=47839 {ECO:0000313|EMBL:CDO90741.1};
RN   [1] {ECO:0000313|EMBL:CDO90741.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44626 {ECO:0000313|EMBL:CDO90741.1};
RX   PubMed=24874681; DOI=10.1128/genomeA.00499-14;
RA   Sassi M., Croce O., Robert C., Raoult D., Drancourt M.;
RT   "Draft Genome Sequence of Mycobacterium triplex DSM 44626.";
RL   Genome Announc. Announc.2:e00499-e00414(2014).
RN   [2] {ECO:0000313|EMBL:CDO90741.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 44626 {ECO:0000313|EMBL:CDO90741.1};
RA   Xu Y.W., Yang Q.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC       {ECO:0000256|RuleBase:RU003557}.
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DR   EMBL; HG964446; CDO90741.1; -; Genomic_DNA.
DR   RefSeq; WP_036471444.1; NZ_LQPY01000046.1.
DR   AlphaFoldDB; A0A024K4C7; -.
DR   STRING; 47839.BN973_05141; -.
DR   eggNOG; COG0183; Bacteria.
DR   HOGENOM; CLU_035425_3_0_11; -.
DR   OrthoDB; 9785768at2; -.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   CDD; cd00829; SCP-x_thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020616; Thiolase_N.
DR   PANTHER; PTHR42870; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR   PANTHER; PTHR42870:SF1; NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2; 1.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW   Transferase {ECO:0000256|RuleBase:RU003557}.
FT   DOMAIN          5..179
FT                   /note="Thiolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00108"
FT   DOMAIN          253..353
FT                   /note="Thiolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02803"
SQ   SEQUENCE   381 AA;  40802 MW;  EC615F727F7B16BC CRC64;
     MTNDVAIIGV GLHPFGRFDK TAMQMGAEAI QSALTDAGVE WKDIQFGFGG SHEVSNPDAV
     TRLVGLTGIT FTNVFNACAT AASAIQQTAD TIRLGKYDIG IAIGLDKHPR GAFTDDPAKL
     ALPQWYAQNG QFVTTKFFGM KANKYLHDHN ISQETLARVA NKNFRNGALN PNAFRRKEIS
     VEEILNSNVL NYPLTQYMFC APDEGAAAVI MCRADIAHKY TDKPVYVRAC EIRTRTFGAY
     EVHATFAPLD EDVSPTVYAS KAAYEAAGIG PEDVDVAQLQ DTDAGNEVIH MAETGLCADG
     EQEKLLADGA TEIHGSMPVN TDGGLIANGE PIGASGLRQM HELVRQLRGE AGERQVPGNP
     RVGLAQVYGA PGTASATILS L
//