ID A0A024Q8G6_9BACI Unreviewed; 469 AA.
AC A0A024Q8G6;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Malate-2H(+)/Na(+)-lactate antiporter {ECO:0000313|EMBL:CDQ38562.1};
GN Name=mleN_1 {ECO:0000313|EMBL:CDQ38562.1};
GN ORFNames=BN990_00833 {ECO:0000313|EMBL:CDQ38562.1};
OS Virgibacillus massiliensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX NCBI_TaxID=1462526 {ECO:0000313|EMBL:CDQ38562.1, ECO:0000313|Proteomes:UP000028875};
RN [1] {ECO:0000313|EMBL:CDQ38562.1, ECO:0000313|Proteomes:UP000028875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Vm-5 {ECO:0000313|EMBL:CDQ38562.1,
RC ECO:0000313|Proteomes:UP000028875};
RA Urmite Genomes U.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000028875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Vm-5 {ECO:0000313|Proteomes:UP000028875};
RA Khelaifia S., Croce O., Lagier J.C., Raoult D.;
RT "Draft genome sequence of Virgibacillus massiliensis Vm-5.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDQ38562.1}.
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DR EMBL; CCDP010000001; CDQ38562.1; -; Genomic_DNA.
DR RefSeq; WP_038242546.1; NZ_CCDP010000001.1.
DR AlphaFoldDB; A0A024Q8G6; -.
DR STRING; 1462526.BN990_00833; -.
DR eggNOG; COG1757; Bacteria.
DR OrthoDB; 9762978at2; -.
DR Proteomes; UP000028875; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR43478; NA+/H+ ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43478:SF1; NA_H_ANTIPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028875};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 179..466
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 469 AA; 50089 MW; BE9A2670A3031E6A CRC64;
MDGASTLGFI SVLPPLIAIV LAFWTRDTIL SLGIACLVGV FLAGEGLLGF PNLMKEALGN
ESFSWIFLLE IFIGILIAFF QRTGAIQSFA DLVGRRQASK KRIGITTWFM GLFVFFSDYF
SPVFVGSTMR KVTDKAKMSR EKLAYICDST SAPVSVIVPI TGWAVFISGL LIGLGPIQNE
ADALDVFTKS IPFNFYAVLS VLLVGLIASG IIKDFGPMRK AEERAHKEGK LVRDGSTPLV
SKELTNIKPF FNDRLLSIAW NFFLPVLLII TIAVGTYIGL GSAKTMEAFL AAVIFLGIIM
RIQGIPVKDI MDTALNGIKG IMPAVMILVF AYTINALNEQ MGTANYLIQT TETWLNPGLL
PAITFLLAAV IAFSTGTSWG TFGIMIPIAV PLALGFAGGE IDTVVLATIA AVAGGGVFGD
HCSPLSDTTI LASTGAAVDH IDHVRTQIPY SMVVGIIGLA IYLGLGLIG
//
