ID A0A024TEG7_9STRA Unreviewed; 852 AA.
AC A0A024TEG7;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=GPI ethanolamine phosphate transferase 3 {ECO:0000256|ARBA:ARBA00020841};
GN ORFNames=H310_13816 {ECO:0000313|EMBL:ETV91757.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV91757.1};
RN [1] {ECO:0000313|EMBL:ETV91757.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETV91757.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
CC {ECO:0000256|ARBA:ARBA00008695}.
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DR EMBL; KI914007; ETV91757.1; -; Genomic_DNA.
DR RefSeq; XP_008879683.1; XM_008881461.1.
DR AlphaFoldDB; A0A024TEG7; -.
DR STRING; 157072.A0A024TEG7; -.
DR EnsemblFungi; H310_13816-t26_1; H310_13816-t26_1-p1; H310_13816.
DR EnsemblProtists; ETV91757; ETV91757; H310_13816.
DR GeneID; 20090866; -.
DR VEuPathDB; FungiDB:H310_13816; -.
DR eggNOG; KOG2126; Eukaryota.
DR OrthoDB; 5479199at2759; -.
DR UniPathway; UPA00196; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051377; F:mannose-ethanolamine phosphotransferase activity; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd16023; GPI_EPT_3; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR InterPro; IPR037675; PIG-O_N.
DR InterPro; IPR045687; PIGG/GPI7_C.
DR InterPro; IPR039524; PIGO/GPI13.
DR PANTHER; PTHR23071:SF1; GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3; 1.
DR PANTHER; PTHR23071; PHOSPHATIDYLINOSITOL GLYCAN; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR Pfam; PF19316; PIGO_PIGG; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 450..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..559
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..634
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 646..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 677..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 753..773
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 785..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 816..836
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 692..830
FT /note="GPI ethanolamine phosphate transferase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19316"
SQ SEQUENCE 852 AA; 94228 MW; A78FF53A72E8E09A CRC64;
MVAGAVVVSF VLHAAAVLLF TNGFFLTRYE AKEVSTCTEE AAVASSMHHH LRRQNGSTSG
CWSNVKFPRV VYIVIDALRY DFMHEASQIE QRQKAKDGGQ YFLNHLPHVH AVLRDRPAHS
LLLRFVADAP TMTMQRLKGL TTGTLPTFLD IKDNMHSEEI VEDSWIKQLT ALNKSIVFMG
DDTWGKLYPT SFLRNYSYDS FNVKDLDTVD NGVLEHFFPE LVNQTDWDVL IAHFLGVDHV
GHTFGPNHPK MQSKLHQMNE FLVELTNTLP SDVLAVVLGD HGMSSDGNHG GATDDETGAA
LFLFSKARPL HALDQDRSMY DVLFDSPNEV AQVDLVPTLS LLMGLPIPFG NLGAVIPNLF
FESTGPGAFN VTDALTHLND ALWVNAHQLR HQFLTTQTIR MDLPAMIQLE KVFAAAQASA
MDAHATHRLL QTYLRDALSL SRALYTQFDL VSMIHGIALQ LAAFVALHFG SFCLRRLPMA
LGVGCFVGFT WPFIASHVSA LLPGAPLPRY LATAGLSTAL LAFRYRPFVS ASTHLSRRSV
GLAMLVVLHC ASLFSNSYLV VQDRVLLFLS ATTVALLGMD ILVQRKWSHL PPFMLLCVVH
RLFAAWPHPN IVFTTVTVQM TWIPMAALGV WICFVHPLSL ISYVCVWLYW FDVFPLFLPW
VVYGWTILHL RQPSSPLLVL VLLHGPSSPG TFALFIAMAT LFHSLDKSPS VPTTVGYCFL
VHTLYFQSGH GNSFASLQNA AAFVGMAKFQ WHIAGVLLAV NTFGAFWLGL ALVPTPATQT
TTVVTGYFTL SAICTTIFVA ICRRHLMVWA IFAPKFVFDA AISVAVHGLV LAQALLGHVE
KSDGDCKMAH LS
//
