ID   A0A024TF19_9STRA        Unreviewed;       918 AA.
AC   A0A024TF19;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=3'-5' exonuclease domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=H310_13432 {ECO:0000313|EMBL:ETV92191.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV92191.1};
RN   [1] {ECO:0000313|EMBL:ETV92191.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETV92191.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI914002; ETV92191.1; -; Genomic_DNA.
DR   RefSeq; XP_008879155.1; XM_008880933.1.
DR   AlphaFoldDB; A0A024TF19; -.
DR   STRING; 157072.A0A024TF19; -.
DR   EnsemblFungi; H310_13432-t26_1; H310_13432-t26_1-p1; H310_13432.
DR   EnsemblProtists; ETV92191; ETV92191; H310_13432.
DR   GeneID; 20090482; -.
DR   VEuPathDB; FungiDB:H310_13432; -.
DR   eggNOG; KOG2207; Eukaryota.
DR   OrthoDB; 54208at2759; -.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd04332; YbaK_like; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   Gene3D; 3.90.960.10; YbaK/aminoacyl-tRNA synthetase-associated domain; 1.
DR   InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR   InterPro; IPR015003; DUF1853.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR036754; YbaK/aa-tRNA-synt-asso_dom_sf.
DR   InterPro; IPR007214; YbaK/aa-tRNA-synth-assoc-dom.
DR   PANTHER; PTHR47765; 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47765:SF2; EXONUCLEASE MUT-7 HOMOLOG; 1.
DR   Pfam; PF01612; DNA_pol_A_exo1; 1.
DR   Pfam; PF08907; DUF1853; 1.
DR   Pfam; PF04073; tRNA_edit; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   SUPFAM; SSF55826; YbaK/ProRS associated domain; 1.
PE   4: Predicted;
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022839}.
FT   DOMAIN          661..712
FT                   /note="3'-5' exonuclease"
FT                   /evidence="ECO:0000259|Pfam:PF01612"
FT   DOMAIN          809..905
FT                   /note="YbaK/aminoacyl-tRNA synthetase-associated"
FT                   /evidence="ECO:0000259|Pfam:PF04073"
FT   REGION          209..229
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   918 AA;  100786 MW;  DBFCE5BD4BC947A4 CRC64;
     MPDFINLGLT AGGETLEGRA GKFQRKLRMC GDATSSASRW LSAHFAPCGN SVILVQSHVI
     FRGYIYYPLA RMSTTSVLPR PILPSAINED HLQGWWTLDF ENDLQRTTPS SSRFAILPKL
     FWLAKVSATR LDDETVSIPG DPGLHLPSIP VLSRDDLFVA VRAHFASSPT AKPLVVAELR
     PCIHETAFEE TSRGAIVNRA MWQPAIAPPA VKTDMPNRSG RRVAADKRAP RPSSSIMVVD
     VNQASDPTEL AQQLRRATRS GARYGTVKAI AQKVLQPLGL RFSIQCILAL VAQEERTDKN
     ETFRIGQLVV DATSAISAQR RNDDGGTLHA ALLTILADET KWWSVRFLVK AKHTLLNEVR
     ASAMESELER NGDVGAMEGV MTRMLEPDHR GKWHMTAVDL CAAYGLPRAE ATASTMLTKL
     LDANDPVAAE AFVLSQQRCT SRTHRLTQTF MRHSKTRTKA AKRLAALFHS ILPSHTPHAA
     NQRPIVNQDH QLTLVQDILA TRLSVHLVET PDDVTSMMHW MDEALMDPNH SPNERLQPTK
     VVIVGLDCEW RPRAFSTKRD TTLDDDSPDL EQIQVIQIAF PHGHVYVLDC MAPSVIDMVV
     PLFRHLSQPW VVVTGFCVSG DLDRLVASHP GLTDVVHSPD FTCVELRRVA VARAKPDDVP
     TVQRMGLAGL AASYLNLRIP KDQQTSDWAV RPLSADQIEY AAMDAHCVRL LLLYFTAGLD
     GPDPVQEPWT ISSSLWTAWR VHLQAYLGEA DVVAAVASLG LSGTFHTLPT QPHCAVDREG
     HTVIKTVAWV VQHAQHHASA AACGRSPVQF LAVLVDLAKT IDVNKLHSFV QSKLGLSSCA
     ISLASERDLL HVFGYGRGAI GPVGLRRPSL VHIVMDASLV HDDAIYCGAG ALHRVVALSP
     LQLLQCPHLN ISTYDVAA
//