ID A0A024TJN1_9STRA Unreviewed; 931 AA.
AC A0A024TJN1;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=H310_11903 {ECO:0000313|EMBL:ETV94204.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV94204.1};
RN [1] {ECO:0000313|EMBL:ETV94204.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETV94204.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KI913986; ETV94204.1; -; Genomic_DNA.
DR RefSeq; XP_008876974.1; XM_008878752.1.
DR AlphaFoldDB; A0A024TJN1; -.
DR EnsemblFungi; H310_11903-t26_19; H310_11903-t26_19-p1; H310_11903.
DR EnsemblProtists; ETV94204; ETV94204; H310_11903.
DR GeneID; 20088953; -.
DR VEuPathDB; FungiDB:H310_11903; -.
DR OrthoDB; 69158at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF98; TO DEHYDRATION PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..931
FT /note="CSC1/OSCA1-like 7TM region domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001534384"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 618..644
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 709..729
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 749..767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 816..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 872..891
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 900..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 221..309
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 631..890
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 931 AA; 104198 MW; D985033594A3F745 CRC64;
MPWPRSRRLW VVLWAGIAFV AAANVETVQI NVPSGSAYGV LNEAIHSIIS ANATVPREVL
VGLRVVGDKN VPDVRPNPVV LLPGTSAANF SIVGRSPGRF LIEWELLSMS TSLTLFNESS
VSFTLSSSGA FVVFVINNQW PTVFYQVGLS AFVLVLGLAF FAWRRMSKSS IPFWGAHVEG
LFQQVPFRTE EMAFPHGHDQ VDPLDAPSLR DRILLFWRLP IADKLVVDRC GVETALCLHF
LRDAGHLFTG LSIFSTVILV PINYVSGGAL TKSYQEATIS NVPLNSHWFW GHVAVCYIAT
VAMLVFVYRY KLTPTTGGET DAMSSQYVLL SKLRLQDSTL VGPRSVFIQA GLPHYITSRM
LHMHLAHHYT PHDVDTVRVV DDLSQVYQIL GRRMALRNEA SRLVHIYGTN SPLPWFLQWC
PGTSCMPSVL DMAYDYAACL PCKRTLKHRD TPVNNDKQAA LVDMEHEIDQ ALRGGVHSGD
FESLDTAVPP PRIQRRLEQI HQELETYPHF QQRKGTGAAF IVFRSTRAKL AFLEQFLATQ
TATTKLKAQV DASFFRVRDT MRQRRQRSPS DYLVDSSHPS PLLTYLPNLL LQPAPEPGDI
RWANLISRPR SLRRAMVLVF YQGITMTILL LFSTPASVLL YINLDPSSPL YTKLLEDNSI
VTGFLRTYVP TLLLVSVNAL LLVALFYLSI FEPWLTETKR MRSLLVKSFV YLVLSSILFP
SIGVTAVYAT TTSSKGNPLN LDQSTHASYV NSFLFNVCSN FFILYLAQLT CLGTVVQVLR
TGERVLYQPW LRGRAITPTE LFEACRPAPF YFGVEYALML SAFLVTLLGT TLSPALVPCG
AIYFYTRVVS TKYNALYVHP KAPGRGHVTR SVLSLVLVSA LLFQIAMALI LSQLGRREQW
VAVVVLVSVT LLILLWWYAI VDSFWTCCPL S
//
