ID A0A024TKJ9_9STRA Unreviewed; 516 AA.
AC A0A024TKJ9;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=CAMK/CAMK1 protein kinase, variant 1 {ECO:0000313|EMBL:ETV94675.1};
GN ORFNames=H310_11660 {ECO:0000313|EMBL:ETV94675.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV94675.1};
RN [1] {ECO:0000313|EMBL:ETV94675.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETV94675.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. CDPK subfamily. {ECO:0000256|ARBA:ARBA00024334}.
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DR EMBL; KI913984; ETV94675.1; -; Genomic_DNA.
DR RefSeq; XP_008876619.1; XM_008878397.1.
DR AlphaFoldDB; A0A024TKJ9; -.
DR EnsemblFungi; H310_11660-t26_6; H310_11660-t26_6-p1; H310_11660.
DR EnsemblProtists; ETV94675; ETV94675; H310_11660.
DR GeneID; 20088710; -.
DR VEuPathDB; FungiDB:H310_11660; -.
DR OrthoDB; 49147at2759; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00051; EFh; 2.
DR CDD; cd05117; STKc_CAMK; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24347:SF446; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24347; SERINE/THREONINE-PROTEIN KINASE; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00054; EFh; 4.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00018; EF_HAND_1; 3.
DR PROSITE; PS50222; EF_HAND_2; 4.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Kinase {ECO:0000313|EMBL:ETV94675.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:ETV94675.1}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..516
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001534386"
FT DOMAIN 44..299
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 361..396
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 397..432
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 436..471
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 473..508
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT BINDING 73
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 516 AA; 57520 MW; 73BD93DF93AD6E2E CRC64;
MRSGWRRVLT AIPLLAATSP WNTAWSEAHT PKPRQRTKSI SDKYEVGKVI GSGGFAVVKL
AKDRTTGVEV AAKFFDMKTA STAEIEAEID MLRWIGTHAN IVSLRDVVYE PTDIIMIMDL
VRGGELFDYI VSQGSITEAD ASRMLREVCL ALQHLHQRGV CHRDLKPENL LLTEVSPDAD
IKIADFGQSL RLPAGSKLTE SPAGGTIVYW APEIIKRAPQ DCAVDMWAFG VLVRLYSSPP
CAYHADRHRR SCTLPSLPGV SNSWYNSLSD EAKDLLSHLL TVDPEKRFTA ADALSHPWMN
PRFRRRLSRR YRDGLSGRLQ AYRRLQQLRA NIVTVLLSQK LHKSPSGKHV VAPHTTDLET
LNQDVYKEVF ALFDEDQSGA ISKHELANVL RALGQQYTPA EIDDIMKAAD VDGDGGISLT
EFTTLVNSSL IQVEQWNDAD LHAAFEIFDV NHDGFISADE LAYVMNVLDK TPISPAELHD
LIQSIDENGD GKIDYKEFST LMQAWLVEGR GQTKGK
//
