ID A0A024TMZ8_9STRA Unreviewed; 757 AA.
AC A0A024TMZ8;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Inward rectifier potassium channel C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=H310_11319 {ECO:0000313|EMBL:ETV94991.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV94991.1};
RN [1] {ECO:0000313|EMBL:ETV94991.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETV94991.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU003822}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003822}.
CC -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel (TC
CC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822}.
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DR EMBL; KI913982; ETV94991.1; -; Genomic_DNA.
DR RefSeq; XP_008876165.1; XM_008877943.1.
DR AlphaFoldDB; A0A024TMZ8; -.
DR STRING; 157072.A0A024TMZ8; -.
DR EnsemblFungi; H310_11319-t26_2; H310_11319-t26_2-p1; H310_11319.
DR EnsemblProtists; ETV94991; ETV94991; H310_11319.
DR GeneID; 20088369; -.
DR VEuPathDB; FungiDB:H310_11319; -.
DR eggNOG; KOG3827; Eukaryota.
DR OrthoDB; 4126787at2759; -.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 2.60.40.1400; G protein-activated inward rectifier potassium channel 1; 2.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR041647; IRK_C.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR PANTHER; PTHR11767; INWARD RECTIFIER POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR11767:SF102; INWARDLY RECTIFYING POTASSIUM CHANNEL 1, ISOFORM F; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR Pfam; PF17655; IRK_C; 2.
DR PRINTS; PR01320; KIRCHANNEL.
DR SUPFAM; SSF81296; E set domains; 2.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|RuleBase:RU003822};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU003822};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958, ECO:0000256|RuleBase:RU003822};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538,
KW ECO:0000256|RuleBase:RU003822};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003822};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003822};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882,
KW ECO:0000256|RuleBase:RU003822}.
FT TRANSMEM 79..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 92..160
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 170..342
FT /note="Inward rectifier potassium channel C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17655"
FT DOMAIN 513..588
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 600..750
FT /note="Inward rectifier potassium channel C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17655"
FT REGION 339..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 84467 MW; FF9414F5A6457226 CRC64;
MPSAATSTPP ATHFDAVGSW RDEWHGVRVE AMPSGGNKHV RFFDTMTANS SFLDSRHHLV
HNPRSTFKDV VYILINMSWA WFTACILGFS ALITVVFALV FHFLCVDTDV FEDAFNLSYQ
SYSTIGFGIL YPRNACGNLA LSMEAFVSMI LLSAISGLVF VRFSKPRATV VFASKCVVQP
YSHHLALVVR VANATRCRHL HQDSILEASF RVNLLRIEER SGTDSTLVLR RYDLPTLQAD
FLAIRRDIQL VHVIDERSPL RRLTETTLAA SDFAIQVDLV GVDSTTQNTV QCQMLYSALQ
VEWGAKFQDM CKVEGVPGNE QWVMDFDQLS TTVPAHVTTP RRPSAALDTG ASPYTTGSPM
LPVLPPRQLT YAKSCQFSIK DEFMQTTGGD LVDQAATMGT QYAGSPGTHH VVDMPPCEPP
STVRPSRTSR RTPDELTESL LFHEMPTVVH SPNRRASVVS SAANVENAPH FDRILPRHVP
LPFSFHTVYT EALKTSWPWI IGYSFVAFIA LNVLFAFVYY LDMDGVSVYD DIRNNNTDFG
VCFYYSVHTL STVGYGAIGP KSSSTYQNFW IMVESTLGIV VITIFTGISW SKFSRPRAHI
EFSNKAVVTH VRDGTRVLLV RALNLRTHGN ISGNAFRVGV TEVNKHTNLR QVHDVDLVNM
TYPSMNVPAT LVHVITSASP FAKFKSIDDF LECNVQMLCL YSGIDHTFST NVYARKMYTS
EDFVVGDHFA DCAEFSPEGG MAVDFDRFHV HERSLGV
//
